SCHEMBL30403242

SCHEMBL30403242

CCOC(=O)c1cc(C(=O)O)[nH]c1C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
MAPT P10636 4/20 0.63
LMNA P02545 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
GAA P10253 2/20 0.58
NPC1 O15118 1/20 0.58
POLB P06746 1/20 0.58
KMT2A Q03164 4/20 0.53
KDM4E B2RXH2 2/20 0.53
MEN1 O00255 3/20 0.52
RXFP1 Q9HBX9 1/20 0.52
TSHR P16473 1/20 0.47
PDE3B Q13370 2/20 0.47
PDE3A Q14432 2/20 0.47
HRH3 Q9Y5N1 1/20 0.46
ATP4A P20648 1/20 0.45
ATP4B P51164 1/20 0.45
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11647465 0.89 ALDH1A1 (0.67) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL10747580 0.80 ALDH1A1 (0.69) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL10879188 0.79 NOTUM (0.55) ALDH1A1MAPTLMNAGAAKDM4E
SCHEMBL23732252 0.79 ALDH1A1 (0.67) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL1157003 0.77 MAPT (0.65) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL9671945 0.77 ALDH1A1 (1.00) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL3023118 0.76 ALDH1A1 (0.54) ALDH1A1MAPTLMNAL3MBTL1NPC1
SCHEMBL15151519 0.75 ALDH1A1 (0.51) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL4876345 0.75 ALDH1A1 (0.76) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL2913063 0.75 ALDH1A1 (0.61) ALDH1A1MAPTLMNAL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116096714-A Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections 安力高医药股份有限公司 2023-05-09 CN disclosed