Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.35 |
| ▸ | TUBB | P07437 | 7/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25421574 | 1.00 | MEN1 (0.36) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL16031335 | 0.83 | STING1 (0.38) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL16156325 | 0.81 | HTR1A (0.36) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL16149538 | 0.79 | HTR1A (0.37) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL25421875 | 0.78 | ALDH1A1 (0.38) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL30405780 | 0.78 | ALDH1A1 (0.38) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL17522629 | 0.73 | PTGDR (0.38) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL993313 | 0.71 | AHR (0.41) | ALDH1A1MAPTHTR1ADRD2ADRB2 | |
| SCHEMBL30295644 | 0.71 | AHR (0.41) | ALDH1A1MAPTHTR1ADRD2ADRB2 | |
| SCHEMBL20504885 | 0.71 | ADRB2 (0.52) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163061-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| CN-118647378-A | Inhibitors of Mei Nen protein interaction with MLL | 巴拉疗法公司 | 2024-09-13 | — | — | CN | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163061-A1 | INHIBITORS OF MENIN-MLL INTERACTION | MLLT1, MEN1, BMI1 | MEN1 2/4885KMT2A 8/4885KDM4E 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.