Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | OGG1 | O15527 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30407567 | 1.00 | FAAH (0.50) | FAAHOGG1TRPV1BCHEKMT2A | |
| SCHEMBL11800819 | 0.84 | BCHE (0.54) | FAAHOGG1TRPV1BCHEALDH1A1 | |
| SCHEMBL11584009 | 0.81 | FAAH (0.56) | FAAHOGG1TRPV1 | |
| SCHEMBL5916715 | 0.80 | BCHE (0.51) | FAAHOGG1BCHEKMT2ARXRA | |
| SCHEMBL7932475 | 0.80 | BCHE (0.51) | FAAHOGG1BCHEKMT2ARXRA | |
| SCHEMBL11798709 | 0.80 | FAAH (0.49) | FAAHOGG1TRPV1BCHEALDH1A1 | |
| SCHEMBL9623340 | 0.80 | OGG1 (0.54) | FAAHOGG1TRPV1BCHEKMT2A | |
| SCHEMBL5702114 | 0.80 | FAAH (0.62) | FAAH | |
| SCHEMBL3884023 | 0.79 | BCHE (0.50) | FAAHOGG1TRPV1BCHEKMT2A | |
| SCHEMBL9671217 | 0.79 | RXRA (0.50) | OGG1BCHEKMT2ARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4167987-A1 | MARC1 INHIBITORS FOR TREATMENT OF LIPID METABOLISM DISORDERS | Christian-Albrechts-Universität zu Kiel (DE) | 2023-04-26 | — | — | EP | disclosed |