Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30408756 | 1.00 | LMNA (0.37) | LMNAMAPTPTPN1HPGDALDH1A1 | |
| SCHEMBL97236 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL11001835 | 0.82 | — | — | |
| Trifluoroacetic Acid SCHEMBL28148714 | 0.76 | MEN1 (0.36) | LMNACHIT1KMT2A | |
| Isovaleramide SCHEMBL5486726 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TDP1CA2 | |
| Trifluoroacetic Acid SCHEMBL6221198 | 0.74 | CHIT1 (0.38) | LMNACHIT1 | |
| Trifluoroacetic Acid SCHEMBL6892922 | 0.72 | CHIT1 (0.40) | LMNACHIT1KMT2A | |
| Trifluoroacetic Acid SCHEMBL29019090 | 0.72 | TP53 (0.38) | LMNAALDH1A1TP53CA2 | |
| Trifluoroacetic Acid SCHEMBL28996861 | 0.71 | CA2 (0.36) | MAPTALDH1A1SMN1; SMN2CA2CHIT1 | |
| Trifluoroacetic Acid SCHEMBL6222069 | 0.71 | CA2 (0.36) | MAPTALDH1A1SMN1; SMN2CA2CHIT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426714-A1 | NOVEL AURISTATIN ANALOGS AND IMMUNOCONJUGATES THEREOF | Adcentrx Therapeutics Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| WO-2023081230-A1 | NOVEL AURISTATIN ANALOGS AND IMMUNOCONJUGATES THEREOF | ADCENTRX THERAPEUTICS INC. (US) | 2023-05-11 | — | — | WO | disclosed |