Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28815924 | 0.90 | RAB9A (0.59) | RAB9AKDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL29802292 | 0.90 | RAB9A (0.59) | RAB9AKDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL23606684 | 0.74 | ALDH1A1 (0.66) | RAB9AKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL29624740 | 0.73 | RAB9A (1.00) | RAB9AKDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL2266526 | 0.73 | RAB9A (1.00) | RAB9AKDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL24164236 | 0.68 | TSHR (0.48) | RAB9AKDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL13085156 | 0.65 | RECQL (0.71) | RAB9AKDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL22577608 | 0.64 | TDO2 (0.67) | RAB9AKDM4ETSHRNPC1ALDH1A1 | |
| SCHEMBL5473377 | 0.64 | RAB9A (0.73) | RAB9AKDM4ETSHRHSD17B10PKM | |
| SCHEMBL25225465 | 0.63 | RAB9A (0.64) | RAB9AKDM4ESMN1; SMN2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116200756-A | Process for preparing fluoromethylated benzimidazolo [2,1-a ] isoquinoline derivatives | 昆明学院 | 2023-06-02 | — | — | CN | disclosed |