Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 6/20 | 0.39 |
| ▸ | LCK | P06239 | 6/20 | 0.39 |
| ▸ | KDR | P35968 | 6/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28983139 | 1.00 | MMP2 (0.46) | MMP2ADAMTS5FASNOGALMNA | |
| SCHEMBL5798538 | 0.73 | PDE3B (0.46) | MMP2ADAMTS5OGALMNACYP3A4 | |
| SCHEMBL7961776 | 0.73 | OGA (0.47) | MMP2ADAMTS5FASNOGALMNA | |
| SCHEMBL30609653 | 0.72 | ADRB1 (0.46) | MMP2ADAMTS5OGACYP3A4CYP2C9 | |
| SCHEMBL15548204 | 0.72 | ADRB1 (0.46) | MMP2ADAMTS5OGACYP3A4CYP2C9 | |
| SCHEMBL23075831 | 0.70 | MMP2 (0.45) | MMP2ADAMTS5FASNOGALMNA | |
| SCHEMBL25667821 | 0.69 | ADAMTS5 (0.48) | MMP2ADAMTS5CYP3A4CYP2C9HTT | |
| SCHEMBL23075769 | 0.68 | CRBN (0.64) | MMP2ADAMTS5CRBNDDB1 | |
| SCHEMBL23075748 | 0.68 | CRBN (0.64) | MMP2ADAMTS5CRBNDDB1 | |
| SCHEMBL23075799 | 0.68 | CRBN (0.46) | MMP2ADAMTS5FASNOGALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768771-A | Arylsulfonyl derivatives and their use as muscarinic acetylcholine receptor M5 inhibitors | 范德堡大学 | 2023-03-07 | — | — | CN | claimed |