Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10379774 | 1.00 | SIGMAR1 (0.51) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| SCHEMBL320896 | 0.78 | IDO1 (0.50) | SLC6A4IDO1PPARGEPHX2SLC6A2 | |
| SCHEMBL13003553 | 0.77 | IDO1 (0.46) | SLC6A4IDO1PPARGEPHX2SLC6A2 | |
| SCHEMBL10561344 | 0.77 | SIGMAR1 (0.56) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| SCHEMBL18893127 | 0.77 | EPHX2 (0.44) | IDO1PPARGEPHX2POLBMAPK1 | |
| Hydrochloric Acid SCHEMBL4680281 | 0.76 | SIGMAR1 (0.55) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| SCHEMBL30184157 | 0.75 | IDO1 (0.47) | SLC6A4IDO1PPARGEPHX2SLC6A2 | |
| SCHEMBL15160740 | 0.75 | IDO1 (0.47) | SLC6A4IDO1PPARGEPHX2SLC6A2 | |
| SCHEMBL4669556 | 0.75 | IDO1 (0.52) | SIGMAR1SLC6A4HTR2AHTR2BIDO1 | |
| SCHEMBL2426168 | 0.75 | IDO1 (0.47) | SLC6A4IDO1PPARGEPHX2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4293009-B1 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | ZOGENIX INTERNATIONAL LTD (GB) | 2025-06-11 | — | — | EP | disclosed |
| EP-3800177-B1 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | ZOGENIX INTERNATIONAL LTD (GB) | 2025-01-29 | — | — | EP | disclosed |
| EP-4293009-A2 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | Zogenix International Limited (GB) | 2023-12-20 | — | — | EP | disclosed |
| US-11634377-B2 | Fenfluramine compositions and methods of preparing the same | ZOGENIX INTERNATIONAL LIMITED (GB) | 2023-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634377-B2 | Fenfluramine compositions and methods of preparing the same | FAAH, FAAH2, TPH1 | SIGMAR1 1220/4885SLC6A4 203/4885LMNA 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.