Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.57 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.39 |
| ▸ | RELA | Q04206 | 5/20 | 0.39 |
| ▸ | FOS | P01100 | 4/20 | 0.39 |
| ▸ | JUN | P05412 | 4/20 | 0.39 |
| ▸ | ATF1 | P18846 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25227768 | 1.00 | SYK (0.57) | SYKSTK17BSTK17AALDH1A1NFKB1 | |
| SCHEMBL25031184 | 0.86 | ALDH1A1 (0.57) | SYKALDH1A1NFKB1NFKB2RELA | |
| SCHEMBL23625406 | 0.77 | SYK (0.50) | SYKALDH1A1NFKB1NFKB2RELA | |
| SCHEMBL14810384 | 0.77 | KDM4E (0.57) | SYKALDH1A1NFKB1NFKB2RELA | |
| SCHEMBL23620399 | 0.77 | SYK (0.54) | SYKALDH1A1NFKB1NFKB2RELA | |
| SCHEMBL2523948 | 0.76 | SYK (0.53) | SYKALDH1A1NFKB1NFKB2RELA | |
| SCHEMBL24851336 | 0.75 | SYK (0.48) | SYKALDH1A1NFKB1NFKB2RELA | |
| SCHEMBL22401330 | 0.75 | STK17B (0.51) | SYKSTK17BSTK17AALDH1A1NFKB1 | |
| SCHEMBL12942870 | 0.75 | SYK (0.64) | SYKSTK17BSTK17AALDH1A1MAPT | |
| SCHEMBL30504113 | 0.75 | STK17B (0.51) | SYKSTK17BSTK17AALDH1A1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066348-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (HK) | 2025-02-27 | — | — | US | disclosed |
| EP-4430049-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023083285-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066348-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | USP1, USP2, USP28 | SYK 3491/4885STK17B 1219/4885STK17A 1307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.