SCHEMBL3041390

SCHEMBL3041390

CN1C(=O)CC(F)(F)c2cc(N3C[C@H](C(N)=O)OC3=O)ccc21

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 8/20 0.47
F10 P00742 3/20 0.36
MAOB P27338 7/20 0.35
LMNA P02545 1/20 0.35
PTGS1 P23219 1/20 0.35
CALML3 P27482 1/20 0.35
SDHA P31040 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3048401 0.89 F10 (0.36) MAOAF10MAOBLMNAPTGS1
SCHEMBL5862835 0.85 MAOA (0.48) MAOAF10MAOBLMNAPTGS1
SCHEMBL3039246 0.82 MAOA (0.56) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL5998601 0.79 MAOA (0.51) MAOAF10MAOBLMNAPTGS1
SCHEMBL3029206 0.78 MAOA (0.47) MAOAF10MAOB
SCHEMBL6686796 0.78 MAOA (0.47) MAOAF10MAOB
SCHEMBL3032928 0.77 MAOA (0.47) MAOAF10MAOBLMNAPTGS1
SCHEMBL3039330 0.77 F10 (0.56) MAOAF10MAOBLMNAPTGS1
SCHEMBL5862218 0.76 MAOA (0.39) MAOAF10MAOBLMNAPTGS1
SCHEMBL3036010 0.76 MAOA (0.46) MAOAF10MAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111638632-B Photoresist reworking liquid composition for CF procedure 福建省佑达环保材料有限公司 2022-08-05 CN claimed
CN-111704963-A Water-based cleaning agent for cleaning liquid crystal 福建省佑达环保材料有限公司 2020-09-25 CN claimed
CN-111638632-A Photoresist reworking liquid composition for CF procedure 福建省佑达环保材料有限公司 2020-09-08 CN claimed
CN-103772064-A Seed dressing containing pyrrolidine methanol derivative ANHUI LAIMUJIA FERTILIZER INDUSTRY CO LTD 2014-05-07 CN claimed
US-20040147760-A1 N-aryl-2-oxazolidinone-5-carboxamides and their derivatives PHARMACIA & UPJOHN COMPANY 2004-07-29 US claimed
CN-111638632-B Photoresist reworking liquid composition for CF procedure 福建省佑达环保材料有限公司 2022-08-05 CN disclosed
CN-111704963-B Water-based cleaning agent for cleaning liquid crystal 福建省佑达环保材料有限公司 2021-06-01 CN disclosed
CN-111704963-A Water-based cleaning agent for cleaning liquid crystal 福建省佑达环保材料有限公司 2020-09-25 CN disclosed
CN-111638632-A Photoresist reworking liquid composition for CF procedure 福建省佑达环保材料有限公司 2020-09-08 CN disclosed
CN-110545850-A Releasable conjugates QUIAPEG PHARMACEUTICALS AB 2019-12-06 CN disclosed
CN-103547558-B Preparation is containing the method for 5-membered ring compounds ONO PHARMACEUTICAL CO.,LTD. (JP) 2016-03-16 CN disclosed
EP-2703381-B1 METHOD FOR PRODUCING FIVE-MEMBERED RING-CONTAINING COMPOUND ONO PHARMACEUTICAL CO (JP) 2015-10-21 EP disclosed
EP-1107969-A2 COLLECTIONS OF COMPOUNDS Spirogen Limited (GB) 2001-06-20 EP disclosed
EP-1107970-A2 COLLECTIONS OF COMPOUNDS Spirogen Limited (GB) 2001-06-20 EP disclosed
CN-1257068-A Process for preparation of condensed sulfamide SHIONOGI & CO (JP) 2000-06-21 CN disclosed
CN-1052474-C Process for preparing sulfamide SHIONOGI SEIYAKU KK (JP) 2000-05-17 CN disclosed
WO-2000012506-A2 COLLECTIONS OF COMPOUNDS SPIROGEN LIMITED (GB) 2000-03-09 WO disclosed
WO-2000012508-A2 PYRROLBENZODIAZEPINES SPIROGEN LIMITED (GB) 2000-03-09 WO disclosed
WO-2000012509-A2 COLLECTIONS OF COMPOUNDS SPIROGEN LIMITED (GB) 2000-03-09 WO disclosed
CN-1078718-A process for preparing sulfamide SHIONOGI & CO (JP) 1993-11-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147760-A1 N-aryl-2-oxazolidinone-5-carboxamides and their derivatives OXA1L, AADAC, MT-ND5 MAOA 957/4885F10 4479/4885MAOB 976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.