SCHEMBL3041544

SCHEMBL3041544

CCOC(=O)c1ccc(C(O)(C(=O)c2ccccc2)c2ccccc2)cc1C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
HPGD P15428 2/20 0.42
HTT P42858 1/20 0.40
ALDH1A1 P00352 8/20 0.40
SMN1; SMN2 Q16637 5/20 0.40
NPC1 O15118 4/20 0.40
POLB P06746 1/20 0.40
RAB9A P51151 3/20 0.40
NPSR1 Q6W5P4 2/20 0.40
NFKB1 P19838 2/20 0.40
NFKB2 Q00653 2/20 0.40
RELA Q04206 2/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
CDC25B P30305 1/20 0.40
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29619268 0.76 TSHR (0.75) TSHRHTTALDH1A1SMN1; SMN2NPC1
SCHEMBL195278 0.76 TSHR (0.75) TSHRHTTALDH1A1SMN1; SMN2NPC1
SCHEMBL14037067 0.76 ALDH1A1 (0.57) TSHRHPGDHTTALDH1A1SMN1; SMN2
SCHEMBL16108187 0.76 TSHR (0.56) TSHRHPGDHTTALDH1A1SMN1; SMN2
SCHEMBL5609240 0.75 TSHR (0.58) TSHRHPGDHTTALDH1A1SMN1; SMN2
Ether SCHEMBL11189868 0.74 CES1 (0.50) HTTALDH1A1SMN1; SMN2NPC1POLB
SCHEMBL247032 0.74 CYP2D6 (0.38) TSHRHPGDHTTALDH1A1POLB
SCHEMBL11627035 0.73 LMNA (0.50) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL4734723 0.72 TSHR (0.54) TSHRHPGDALDH1A1SMN1; SMN2NPC1
SCHEMBL4733091 0.71 TSHR (0.53) TSHRHPGDHTTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2107092-B1 Pressure-sensitive adhesive composition, pressure-sensitive adhesive sheets, and surface protecting film NITTO DENKO CORP (JP) 2012-06-27 EP disclosed
EP-2258782-A2 Pressure-sensitive adhesive composition, pressure-sensitive adhesive sheets, and surface protecting film NITTO DENKO CORPORATION (JP) 2010-12-08 EP disclosed
EP-2241604-A1 Pressure-sensitive adhesive composition, pressure-sensitive adhesive sheets, and surface protecting film NITTO DENKO CORPORATION (JP) 2010-10-20 EP disclosed