Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29228625 | 1.00 | L3MBTL1 (0.50) | L3MBTL1MAP2K1METAP1CASP6ECE1 | |
| SCHEMBL69177 | 0.82 | L3MBTL1 (0.64) | L3MBTL1MAP2K1 | |
| SCHEMBL30417625 | 0.81 | KDM4E (0.49) | L3MBTL1METAP1CASP6ECE1 | |
| SCHEMBL29228617 | 0.81 | KDM4E (0.49) | L3MBTL1METAP1CASP6ECE1 | |
| SCHEMBL28758910 | 0.81 | SLC6A3 (0.48) | MAP2K1 | |
| SCHEMBL2887102 | 0.80 | CHEK2 (0.43) | METAP1CASP6 | |
| SCHEMBL2496193 | 0.80 | HCRTR1 (0.45) | L3MBTL1ECE1 | |
| SCHEMBL30416661 | 0.79 | SLC6A9 (0.39) | METAP1CASP6 | |
| SCHEMBL29228590 | 0.77 | KMT2A (0.50) | L3MBTL1ECE1 | |
| SCHEMBL7812554 | 0.76 | L3MBTL1 (0.57) | L3MBTL1MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843879-B | Benzothiazole derivatives as DYRK1 inhibitors | 药物治疗股份有限公司 | 2023-05-02 | — | — | CN | disclosed |