Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 3/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744749 | 0.86 | ALOX15 (0.65) | ALOX15P2RY12DHODHALDH1A1HPGD | |
| SCHEMBL9378807 | 0.81 | ALOX15 (0.66) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL30421133 | 0.81 | ALOX15 (0.66) | ALOX15ALDH1A1HPGDHSD17B10MGAM | |
| SCHEMBL18528819 | 0.81 | ALOX15 (0.70) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL31389285 | 0.81 | ALOX15 (0.70) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL18528799 | 0.81 | ALOX15 (0.61) | ALOX15P2RY12DHODHALDH1A1HPGD | |
| SCHEMBL2908552 | 0.80 | ALOX15 (0.64) | ALOX15 | |
| SCHEMBL30438115 | 0.80 | ALOX15 (0.64) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL31389237 | 0.80 | ALOX15 (0.64) | ALOX15 | |
| SCHEMBL9384536 | 0.79 | ALOX15 (0.62) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511731-B | Olefin compounds as modulators of the farnesol X receptor | 百时美施贵宝公司 | 2023-05-23 | — | — | CN | claimed |
| CN-111278817-B | Polycyclic compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-05-16 | — | — | CN | claimed |