Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11592822 | 1.00 | EPHX1 (0.53) | EPHX1NAAAALDH1A1HTTSOAT1 | |
| SCHEMBL3110206 | 1.00 | EPHX1 (0.53) | EPHX1NAAAALDH1A1HTTSOAT1 | |
| SCHEMBL4630680 | 1.00 | EPHX1 (0.53) | EPHX1NAAAALDH1A1HTTSOAT1 | |
| SCHEMBL11591470 | 1.00 | EPHX1 (0.53) | EPHX1NAAAALDH1A1HTTSOAT1 | |
| SCHEMBL11591733 | 1.00 | EPHX1 (0.53) | EPHX1NAAAALDH1A1HTTSOAT1 | |
| SCHEMBL11593452 | 1.00 | EPHX1 (0.53) | EPHX1NAAAALDH1A1HTTSOAT1 | |
| SCHEMBL1078177 | 0.98 | EPHX1 (0.56) | EPHX1NAAAALDH1A1HTTSOAT1 | |
| SCHEMBL305155 | 0.98 | ALDH1A1 (0.50) | EPHX1NAAAALDH1A1HTTSOAT1 | |
| SCHEMBL8375449 | 0.94 | ALDH1A1 (0.50) | EPHX1NAAAALDH1A1HTTSOAT1 | |
| SCHEMBL4640870 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1981 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373994-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF | ST PHARM CO., LTD. (KR) | 2023-11-23 | — | — | US | claimed |
| EP-4201405-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF | ST Pharm Co., Ltd. (KR) | 2023-06-28 | — | — | EP | claimed |
| US-11234966-B2 | C5-substituted carbapenem antibiotics, compositions containing such compounds, and methods of use in treatment of mycobacterium tuberculosis and non-tubercular mycobacteria | SOUTHERN METHODIST UNIVERSITY (US) | 2022-02-01 | — | — | US | claimed |
| US-20200339582-A1 | Atypical Carbapenem Antibiotics with Improved Activity Against Carbapenemase-Producing Acinetobacter baumannii | BUYNAK JOHN (US) | 2020-10-29 | — | — | US | claimed |
| US-20200281894-A1 | C5-SUBSTITUTED CARBAPENEM ANTIBIOTICS, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF USE IN TREATMENT OF MYCOBACTERIUM TUBERCULOSIS AND NON-TUBERCULAR MYCOBACTERIA | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2020-09-10 | — | — | US | claimed |
| US-10702501-B2 | C5-substituted carbapenem antibiotics, compositions containing such compounds, and methods of use in treatment of Mycobacterium tuberculosis and non-tubercular mycobacteria | SOUTHERN METHODIST UNIVERSITY (US) | 2020-07-07 | — | — | US | claimed |
| US-20180353476-A1 | C5-SUBSTITUTED CARBAPENEM ANTIBIOTICS, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF USE IN TREATMENT OF MYCOBACTERIUM TUBERCULOSIS AND NON-TUBERCULAR MYCOBACTERIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-12-13 | — | — | US | claimed |
| CN-207405107-U | A kind of process units of tert-butylcyclohexyl ethyl carbonate synthetic perfume | 安徽华业香料合肥有限公司 | 2018-05-25 | — | — | CN | claimed |
| CN-102558181-B | Preparation method of carbapenems | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY SHIJIAZHUAN | 2015-04-22 | — | — | CN | claimed |
| US-8658639-B2 | N-substituted-cyclic amino derivative | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-02-25 | — | — | US | claimed |
| EP-0497978-A1 | CEPHALOSPORIN COMPOUNDS AND PRODUCTION THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1992-08-12 | — | — | EP | claimed |
| EP-0495953-A1 | 10-(1-Hydoxyethyl)-11-oxo-1-azatricyclo(7.2.0.0(3,8)undec-2-ene-2-carboxylic acid esters and a process for preparing thereof. | GLAXO SPA (IT) | 1992-07-29 | — | — | EP | claimed |
| EP-0484966-A2 | 7-Acyl-3-(substituted carbamoyloxy) cephem compounds, use thereof and process for their preparation | Eisai Co., Ltd. (JP) | 1992-05-13 | — | — | EP | claimed |
| WO-1992003437-A1 | 10(1-HYDROXYETHYL)-11-OXO-1-AZATRICYCLO[7.2.0.0.3.8]UNDEC-2-ENE-2-CARBOXYLIC ACID ESTERS AND A PROCESS FOR PREPARING THEREOF | GLAXO S.P.A. (IT) | 1992-03-05 | — | — | WO | claimed |
| WO-1992003444-A1 | PENEM COMPOUNDS | SUNTORY LIMITED (JP) | 1992-03-05 | — | — | WO | claimed |
| US-4874856-A | ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1989-10-17 | — | — | US | claimed |
| EP-0307872-A2 | Esters of amino-acids, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | claimed |
| EP-0304036-A2 | 3-(substituted)propenyl-7-(aminothiazolylacetamido)ceph-3-em-4-carboxylic acids and esters thereof | Bristol-Myers Squibb Company (US) | 1989-02-22 | — | — | EP | claimed |
| US-4731362-A | Alkylcarbamoyloxymethylcephem compounds | SHIONOGI & CO., LTD. (JP) | 1988-03-15 | — | — | US | claimed |
| EP-0005793-A1 | Process for the preparation of trans-4-alkyl-cyanoarylcyclohexanes | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1979-12-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10702501-B2 | C5-substituted carbapenem antibiotics, compositions containing such compounds, and methods of use in treatment of Mycobacterium tuberculosis and non-tubercular mycobacteria | C5, C3AR1, C1R | EPHX1 2409/4885NAAA 624/4885ALDH1A1 2602/4885 |
| US-20200281894-A1 | C5-SUBSTITUTED CARBAPENEM ANTIBIOTICS, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF USE IN TREATMENT OF MYCOBACTERIUM TUBERCULOSIS AND NON-TUBERCULAR MYCOBACTERIA | C5, C3AR1, C1R | EPHX1 2409/4885NAAA 624/4885ALDH1A1 2602/4885 |
| US-11234966-B2 | C5-substituted carbapenem antibiotics, compositions containing such compounds, and methods of use in treatment of mycobacterium tuberculosis and non-tubercular mycobacteria | C5, C3AR1, C1R | EPHX1 2409/4885NAAA 624/4885ALDH1A1 2602/4885 |
| US-20180353476-A1 | C5-SUBSTITUTED CARBAPENEM ANTIBIOTICS, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF USE IN TREATMENT OF MYCOBACTERIUM TUBERCULOSIS AND NON-TUBERCULAR MYCOBACTERIA | C5, C3AR1, C1R | EPHX1 2409/4885NAAA 624/4885ALDH1A1 2602/4885 |
| US-20230373994-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF | PYCR1, PIN1, QDPR | EPHX1 2293/4885NAAA 3359/4885ALDH1A1 998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.