Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.61 |
| ▸ | CYCS | P99999 | 4/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 5/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9639860 | 1.00 | TOP1 (0.61) | TOP1CYCSENPP2TERTABCG2 | |
| Acetic Acid SCHEMBL9850523 | 0.97 | TOP1 (0.61) | TOP1CYCSENPP2TERTABCG2 | |
| Acetic Acid SCHEMBL9639956 | 0.92 | TOP1 (0.67) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL30363117 | 0.87 | TOP1 (0.62) | TOP1CYCSENPP2TERTSTAT3 | |
| SCHEMBL10471408 | 0.86 | TOP1 (0.58) | TOP1CYCSENPP2TERTABCG2 | |
| Hydrochloric Acid SCHEMBL30306704 | 0.85 | TOP1 (0.60) | TOP1CYCSENPP2TERTSTAT3 | |
| Hydrochloric Acid SCHEMBL599425 | 0.85 | TOP1 (0.60) | TOP1CYCSENPP2TERTSTAT3 | |
| SCHEMBL16552331 | 0.85 | TOP1 (0.71) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL30136 | 0.85 | TOP1 (0.64) | TOP1CYCSENPP2TERTSTAT3 | |
| SCHEMBL29405434 | 0.85 | TOP1 (0.64) | TOP1CYCSENPP2TERTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12012426-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2024-06-18 | — | — | US | disclosed |
| US-20230219983-A1 | TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2023-07-13 | — | — | US | disclosed |
| US-11639362-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219983-A1 | TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME | ADH4, ADH5, PF4 | TOP1 4076/4885CYCS 2027/4885ENPP2 1199/4885 |
| US-12012426-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | ADH4, ADH5, PF4 | TOP1 4076/4885CYCS 2027/4885ENPP2 1199/4885 |
| US-11639362-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | ADH4, ADH5, PF4 | TOP1 4076/4885CYCS 2027/4885ENPP2 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.