Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | SNCA | P37840 | 4/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | DNM2 | P50570 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30426569 | 0.97 | APP (0.47) | APPSNCAENPP2ALDH1A1KDM4E | |
| SCHEMBL30427271 | 0.94 | APP (0.48) | APPSNCAENPP2ALDH1A1KDM4E | |
| SCHEMBL25807377 | 0.93 | APP (0.47) | APPSNCAENPP2ALDH1A1KDM4E | |
| SCHEMBL30483203 | 0.93 | APP (0.47) | APPSNCAENPP2ALDH1A1KDM4E | |
| SCHEMBL30426683 | 0.91 | APP (0.47) | APPSNCAENPP2ALDH1A1KDM4E | |
| SCHEMBL31169579 | 0.91 | APP (0.48) | APPSNCAENPP2ALDH1A1KDM4E | |
| SCHEMBL30483276 | 0.91 | APP (0.48) | APPSNCAENPP2ALDH1A1KDM4E | |
| SCHEMBL25807334 | 0.91 | APP (0.48) | APPSNCAENPP2ALDH1A1KDM4E | |
| SCHEMBL20615236 | 0.91 | APP (0.49) | APPSNCAENPP2ALDH1A1KDM4E | |
| SCHEMBL29395523 | 0.91 | APP (0.49) | APPSNCAENPP2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327400-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-10-03 | — | — | US | disclosed |
| EP-4172158-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | The Regents of the University of California (US) | 2023-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327400-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, PDK1 | APP 2860/4885SNCA 4854/4885ENPP2 2354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.