Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 6/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30429215 | 0.95 | PGR (0.33) | PRKCIPGRKDM4EALDH1A1MAPT | |
| SCHEMBL28545999 | 0.81 | PGR (0.46) | PGRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL19301845 | 0.71 | AR (0.47) | PGRKDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL31263971 | 0.68 | DRD3 (0.36) | KDM4EALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL19301847 | 0.68 | SIGMAR1 (0.39) | PGR | |
| SCHEMBL2955486 | 0.68 | — | — | |
| SCHEMBL14859724 | 0.67 | EPHX2 (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL22366341 | 0.67 | AR (0.34) | AR | |
| SCHEMBL19301778 | 0.66 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL19301772 | 0.65 | GABRA1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511750-B | Macrocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2023-06-13 | — | — | CN | disclosed |