SCHEMBL30429663

SCHEMBL30429663

COc1ccn2c(C[C@@H](C)N(C)C)cnc2c1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 2/20 0.38
KIT P10721 4/20 0.37
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
FLT3 P36888 4/20 0.36
GPR139 Q6DWJ6 1/20 0.35
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25209286 1.00 CSF1R (0.38) CSF1RKITPRMT5WDR77FLT3
SCHEMBL25294274 0.84 TAAR1 (0.44) CSF1RKITPRMT5WDR77HTR2A
SCHEMBL25196657 0.84 GPR139 (0.39) CSF1RKITPRMT5WDR77FLT3
SCHEMBL25247711 0.81 CYP11B1 (0.34) PRMT5WDR77FLT3
SCHEMBL30429657 0.79 HTR2A (0.33) HTR2A
SCHEMBL25199418 0.79 HTR2A (0.33) HTR2A
SCHEMBL23114698 0.79 FLT3 (0.42) CSF1RKITPRMT5WDR77FLT3
SCHEMBL25521003 0.78 DNMT1 (0.41) GPR139HTR2A
SCHEMBL25206395 0.78 PRMT5 (0.37) CSF1RKITPRMT5WDR77FLT3
SCHEMBL30429613 0.78 PRMT5 (0.37) CSF1RKITPRMT5WDR77FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4423060-A2 PSYCHOPLASTOGENIC N-SUBSTITUTED INDOLES Terran Biosciences, Inc. (US) 2024-09-04 EP disclosed
WO-2023077127-A2 N-SUBSTITUTED INDOLES TERRAN BIOSCIENCES, INC. (US) 2023-05-04 WO disclosed