SCHEMBL30429613

SCHEMBL30429613

COc1ccn2c(C[C@@H](C)OS(C)(=O)=O)cnc2c1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
CSF1R P07333 2/20 0.35
GPR139 Q6DWJ6 4/20 0.35
KIT P10721 3/20 0.35
FLT3 P36888 4/20 0.34
RIPK2 O43353 2/20 0.33
ADORA3 P0DMS8 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25206395 1.00 PRMT5 (0.37) PRMT5WDR77CSF1RGPR139KIT
SCHEMBL25195566 0.81 SMN1; SMN2 (0.33) KDM4EALDH1A1HPGD
SCHEMBL30461647 0.80 GPR139 (0.37) PRMT5WDR77CSF1RGPR139KIT
SCHEMBL25197715 0.80 GPR139 (0.37) PRMT5WDR77CSF1RGPR139KIT
SCHEMBL25196657 0.80 GPR139 (0.39) PRMT5WDR77CSF1RGPR139KIT
SCHEMBL25294274 0.80 TAAR1 (0.44) PRMT5WDR77CSF1RKIT
SCHEMBL30429663 0.78 CSF1R (0.38) PRMT5WDR77CSF1RGPR139KIT
SCHEMBL25209286 0.78 CSF1R (0.38) PRMT5WDR77CSF1RGPR139KIT
SCHEMBL23114698 0.75 FLT3 (0.42) PRMT5WDR77CSF1RGPR139KIT
SCHEMBL25199208 0.72 PRMT5 (0.40) PRMT5WDR77CSF1RGPR139KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4423060-A2 PSYCHOPLASTOGENIC N-SUBSTITUTED INDOLES Terran Biosciences, Inc. (US) 2024-09-04 EP disclosed
US-20230159456-A1 N-SUBSTITUTED INDOLES TERRAN BIOSCIENCES INC (US) 2023-05-25 US disclosed
WO-2023077127-A2 N-SUBSTITUTED INDOLES TERRAN BIOSCIENCES, INC. (US) 2023-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159456-A1 N-SUBSTITUTED INDOLES TPH2, TPH1, AANAT PRMT5 661/4885WDR77 2728/4885CSF1R 4254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.