SCHEMBL30429657

SCHEMBL30429657

COc1ccn2c(C[C@@H](C)N(C)C)ncc2c1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.33
VCP P55072 1/20 0.33
KDM4E B2RXH2 3/20 0.32
ALDH1A1 P00352 3/20 0.32
HPGD P15428 3/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32
PKM P14618 1/20 0.31
TAAR1 Q96RJ0 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25199418 1.00 HTR2A (0.33) HTR2AVCPKDM4EALDH1A1HPGD
SCHEMBL25792125 0.86 KDM4E (0.35) HTR2AVCPKDM4EALDH1A1HPGD
SCHEMBL25791379 0.84 TAAR1 (0.44) HTR2ATAAR1
SCHEMBL25195409 0.84 PKM (0.37) HTR2AVCPKDM4EALDH1A1HPGD
SCHEMBL25791549 0.82 DNMT1 (0.39) KDM4EALDH1A1HPGDL3MBTL1MAPT
SCHEMBL25791275 0.81
SCHEMBL25206802 0.80 HTR2A (0.35) HTR2ATAAR1
SCHEMBL25791467 0.80
SCHEMBL25209286 0.79 CSF1R (0.38) HTR2A
SCHEMBL30429663 0.79 CSF1R (0.38) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138948-A1 N-SUBSTITUTED INDOLES AS 5-HYDROXYTRYPTAMINE (5-HT) SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS TERRAN BIOSCIENCES INC (US) 2026-05-21 US disclosed
US-20260078090-A1 N-SUBSTITUTED INDOLES AS 5-HYDROXYTRYPTAMINE (5-HT) SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS TERRAN BIOSCIENCES INC. 2026-03-19 US disclosed
EP-4423060-A2 PSYCHOPLASTOGENIC N-SUBSTITUTED INDOLES Terran Biosciences, Inc. (US) 2024-09-04 EP disclosed
US-20230159456-A1 N-SUBSTITUTED INDOLES TERRAN BIOSCIENCES INC (US) 2023-05-25 US disclosed
WO-2023077127-A2 N-SUBSTITUTED INDOLES TERRAN BIOSCIENCES, INC. (US) 2023-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078090-A1 N-SUBSTITUTED INDOLES AS 5-HYDROXYTRYPTAMINE (5-HT) SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS HTR1D, TPH1, HTR3D HTR2A 13/4885VCP 4744/4885KDM4E 963/4885
US-20260138948-A1 N-SUBSTITUTED INDOLES AS 5-HYDROXYTRYPTAMINE (5-HT) SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS HTR1D, HTR2C, TPH1 HTR2A 14/4885VCP 4229/4885KDM4E 1220/4885
US-20230159456-A1 N-SUBSTITUTED INDOLES TPH2, TPH1, AANAT HTR2A 13/4885VCP 4330/4885KDM4E 3029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.