Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28202713 | 0.79 | BCAT2 (0.46) | PKMBCAT2KMT2AMAPK8MAPK10 | |
| SCHEMBL22004182 | 0.79 | KMT2A (0.59) | KMT2AMAPK8MAPK10ALDH1A1MAPT | |
| SCHEMBL27896300 | 0.79 | PKM (0.44) | PKMBCAT2KMT2AMAPK8MAPK10 | |
| SCHEMBL15575400 | 0.76 | BCAT2 (0.46) | PKMBCAT2KMT2AMAPK8MAPK10 | |
| SCHEMBL2279587 | 0.73 | BCAT2 (0.47) | PKMBCAT2KMT2AMAPK8MAPK10 | |
| SCHEMBL1379773 | 0.71 | KMT2A (0.68) | PKMBCAT2KMT2AMAPK8ALDH1A1 | |
| SCHEMBL3077087 | 0.69 | PKM (0.43) | PKMBCAT2KMT2AMAPK8MAPK10 | |
| SCHEMBL1373806 | 0.69 | — | — | |
| SCHEMBL28517343 | 0.68 | BCAT2 (0.46) | PKMBCAT2KMT2AMAPK8MAPK10 | |
| SCHEMBL7415977 | 0.68 | GSK3B (0.40) | PKMKMT2AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122756-A2 | ULK1 AND ULK2 INHIBITORS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2023-06-29 | — | — | WO | disclosed |