SCHEMBL304334

SCHEMBL304334

Cn1cc(C(=O)Nc2cc(F)ccc2-c2ccc(Cl)c(Cl)c2)c(C(F)F)n1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 4/20 0.42
CSNK1D P48730 6/20 0.40
CSNK1E P49674 6/20 0.40
ALOX15 P16050 1/20 0.39
LMNA P02545 1/20 0.39
THRB P10828 1/20 0.39
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
NPY1R P25929 1/20 0.37
NPY2R P49146 1/20 0.37
IRAK4 Q9NWZ3 2/20 0.37
EIF4E P06730 2/20 0.37
PSEN1 P49768 1/20 0.37
PSEN2 P49810 1/20 0.37
APH1B Q8WW43 1/20 0.37
NCSTN Q92542 1/20 0.37
APH1A Q96BI3 1/20 0.37
PSENEN Q9NZ42 1/20 0.37
APP P05067 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437140 1.00 CHRM3 (0.42) CHRM3CSNK1DCSNK1EALOX15LMNA
SCHEMBL1144969 0.93 CHRM3 (0.43) CHRM3CSNK1DCSNK1ECHRM2CHRM1
SCHEMBL29349968 0.92 CHRM3 (0.51) CHRM3ALOX15LMNATHRBCHRM2
SCHEMBL29445383 0.92 CHRM3 (0.51) CHRM3ALOX15LMNATHRBCHRM2
SCHEMBL68043 0.92 CHRM3 (0.51) CHRM3ALOX15LMNATHRBCHRM2
SCHEMBL3747983 0.91 LMNA (0.42) CHRM3CSNK1DCSNK1ELMNAIRAK4
SCHEMBL3738708 0.89 CHRM3 (0.42) CHRM3CSNK1DCSNK1ELMNATHRB
SCHEMBL567351 0.89 CHRM3 (0.47) CHRM3LMNAIRAK4
SCHEMBL1144790 0.88 CSNK1D (0.43) CHRM3CSNK1DCSNK1ELMNATHRB
SCHEMBL21069195 0.86 IRAK4 (0.40) CHRM3CSNK1DCSNK1ELMNAIRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 631 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827897-B2 Agricultural compositions and related methods FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2023-11-28 US claimed
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
EP-3381289-B1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND BAYER CROPSCIENCE LP (US) 2021-05-05 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
EP-2292098-B1 Combinations comprising a fungicidal strain and at least one additional fungicide BAYER CROPSCIENCE LP (US) 2019-11-06 EP claimed
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
EP-3381289-A1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND Bayer Cropscience LP (US) 2018-10-03 EP claimed
US-20170318816-A1 Combinations Comprising a Fungicidal Strain and an Active Compound BAYER CROPSCIENCE LP 2017-11-09 US claimed
EP-3240406-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2017-11-08 EP claimed
WO-2008092818-A2 PESTICIDAL MIXTURES BASF SE (DE) 2008-08-07 WO claimed
WO-2008071714-A1 MIXTURES COMPRISING 1-METHYLCYCLOPROPENE ROHM AND HAAS COMPANY (US) 2008-06-19 WO claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
EP-1819223-B1 USE OF MENADIONE FOR BOOSTING THE EFFECTIVENESS OF AGROCHEMICALS BASF SE (DE) 2008-03-12 EP claimed
US-20080039320-A1 Use Of Menadione BASF AKTIENGESELLSCHAFT (DE) 2008-02-14 US claimed
WO-2007122264-A2 COMPOSITION COMPRISING A GLUCAN OR A GLUCAN DERIVATIVE AND A PESTICIDE AND METHODS FOR IMPROVING PLANT HEALTH BASF SE (DE) 2007-11-01 WO claimed
EP-1849364-A1 Composition comprising a glucan or a glucan derivative and a pesticide and methods for improving plant health BASF AKTIENGESELLSCHAFT (DE) 2007-10-31 EP claimed
WO-2007104669-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2007-09-20 WO claimed
WO-2007104658-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2007-09-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080039320-A1 Use Of Menadione MANBA, MGAM2, MGAM CHRM3 543/4885CSNK1D 2350/4885CSNK1E 1974/4885
US-20170318816-A1 Combinations Comprising a Fungicidal Strain and an Active Compound O60361, SPOUT1, FBL CHRM3 2648/4885CSNK1D 1477/4885CSNK1E 2210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.