Candidusin C

Candidusin C

SCHEMBL30433698

COc1ccc(-c2cc(OC)c3c(oc4cc(O)c(O)cc43)c2OC)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.56
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.46
CYP3A4 P08684 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 2/20 0.46
KLK7 P49862 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
SLC22A2 O15244 1/20 0.44
SLC22A1 O15245 1/20 0.44
EED O75530 1/20 0.44
ALOX5 P09917 1/20 0.44
THRB P10828 1/20 0.44
G6PD P11413 1/20 0.44
CBR1 P16152 1/20 0.44
APEX1 P27695 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Candidusin A SCHEMBL30692332 0.91 ACHE (0.67) ACHEALDH1A1MAPTRAB9AMEN1
SCHEMBL30583109 0.82 ACHE (0.58) ACHEALDH1A1MAPTMEN1KMT2A
6'-Desmethylcandidusin B SCHEMBL31410089 0.79 ACHE (0.56) ACHEMAPTMEN1KMT2AALOX5
SCHEMBL31410072 0.69 ACHE (0.81) ACHEMAPTMEN1KMT2AALOX5
SCHEMBL27369266 0.67 RAB9A (0.55) ALDH1A1MAPTCYP3A4MAPK1RAB9A
Formonetin SCHEMBL4728656 0.65 RAB9A (0.83) ALDH1A1MAPTCYP3A4MAPK1RAB9A
SCHEMBL17625718 0.65 BACE1 (0.63) ALDH1A1CYP3A4MAPK1RAB9AMEN1
SCHEMBL10579363 0.65 ESR2 (0.60) MAPTMAPK1RAB9AMEN1KMT2A
SCHEMBL6365437 0.64 ACHE (0.80) ACHEALDH1A1MAPTCYP3A4MAPK1
SCHEMBL2344202 0.64 CYP3A4 (0.65) ALDH1A1MAPTCYP3A4MAPK1SLC22A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116064244-B Marine aspergillus ITBBc1, and separated terphenyl compound and application thereof 中国热带农业科学院热带生物技术研究所 2024-02-20 CN disclosed
CN-116064244-A Marine aspergillus ITBBc1, and separated terphenyl compound and application thereof 中国热带农业科学院热带生物技术研究所 2023-05-05 CN disclosed