6'-Desmethylcandidusin B

6'-Desmethylcandidusin B

SCHEMBL31410089

COc1c(-c2ccc(O)c(O)c2)cc(O)c2c1oc1cc(O)c(O)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.56
KDR P35968 2/20 0.53
BCL2 P10415 1/20 0.49
PREP P48147 1/20 0.47
CELA1 Q9UNI1 1/20 0.47
APP P05067 1/20 0.46
GAA P10253 3/20 0.46
MGAM O43451 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
ALOX5 P09917 1/20 0.46
KDM4E B2RXH2 2/20 0.45
MEN1 O00255 2/20 0.45
POLB P06746 2/20 0.45
MAPT P10636 2/20 0.45
APEX1 P27695 2/20 0.45
RECQL P46063 2/20 0.45
BLM P54132 2/20 0.45
KMT2A Q03164 2/20 0.45
NPC1 O15118 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31410072 0.83 ACHE (0.81) ACHEKDRGAAMGAMSI
Candidusin A SCHEMBL30692332 0.80 ACHE (0.67) ACHEKDRPREPCELA1GAA
Candidusin C SCHEMBL30433698 0.79 ACHE (0.56) ACHEKDRPREPCELA1ALOX5
SCHEMBL14259678 0.73 TUBB4A (0.74) APPGAAALOX5KDM4EMEN1
SCHEMBL30583109 0.70 ACHE (0.58) ACHEGAAMGAMSIMGAM2
SCHEMBL29435849 0.66 BCL2 (1.00) BCL2GAAKDM4EMEN1POLB
SCHEMBL30851559 0.66 EGFR (0.60) KDRGAAKDM4EMEN1RECQL
SCHEMBL26114003 0.66 BCL2 (1.00) BCL2GAAKDM4EMEN1POLB
SCHEMBL34716 0.65 KDM4E (0.73) ACHEAPPGAAKDM4EMEN1
SCHEMBL20524674 0.65 ALDH1A1 (0.63) BCL2APPGAAALOX5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119386002-A New medical application of p-terphenyl derivative 华北制药集团新药研究开发有限责任公司 2025-02-07 CN disclosed