Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.80 |
| ▸ | PLK1 | P53350 | 1/20 | 0.80 |
| ▸ | BACE1 | P56817 | 1/20 | 0.80 |
| ▸ | APP | P05067 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | PPARG | P37231 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.68 |
| ▸ | FLT3 | P36888 | 3/20 | 0.67 |
| ▸ | CDK8 | P49336 | 2/20 | 0.64 |
| ▸ | CDK9 | P50750 | 2/20 | 0.64 |
| ▸ | GABRP | O00591 | 1/20 | 0.64 |
| ▸ | GABRD | O14764 | 1/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.64 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359647 | 0.91 | ACHE (0.81) | ACHEPLK1BACE1APPPPARG | |
| Moslosooflavone SCHEMBL6070206 | 0.89 | ACHE (1.00) | ACHEPLK1BACE1APPALDH1A1 | |
| Moslosooflavone SCHEMBL29822243 | 0.89 | ACHE (1.00) | ACHEPLK1BACE1APPALDH1A1 | |
| SCHEMBL29358951 | 0.89 | APP (0.93) | ACHEPLK1BACE1APPALDH1A1 | |
| SCHEMBL1476458 | 0.89 | APP (0.66) | ACHEPLK1BACE1APPALDH1A1 | |
| SCHEMBL31238014 | 0.88 | ALDH1A1 (0.73) | ACHEPLK1BACE1APPALDH1A1 | |
| SCHEMBL987020 | 0.88 | ALDH1A1 (0.73) | ACHEPLK1BACE1APPALDH1A1 | |
| SCHEMBL16894632 | 0.88 | ACHE (0.76) | ACHEPLK1BACE1APPALDH1A1 | |
| SCHEMBL4057928 | 0.88 | ACHE (0.76) | ACHEPLK1BACE1ALDH1A1MAPK1 | |
| SCHEMBL4272626 | 0.85 | ACHE (0.65) | ACHEPLK1BACE1APPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050181080-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2005-08-18 | — | — | US | disclosed |
| US-20030165533-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2003-09-04 | — | — | US | disclosed |
| US-20030152588-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2003-08-14 | — | — | US | disclosed |