Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3029012 | 0.88 | LMNA (0.53) | MCHR1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL14222519 | 0.87 | MEN1 (0.54) | MCHR1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL3033257 | 0.85 | ALDH1A1 (0.48) | MCHR1ALDH1A1KDM4ETDP1HTT | |
| SCHEMBL3033033 | 0.82 | CYP3A4 (0.49) | MCHR1ALDH1A1KDM4ETDP1HTT | |
| SCHEMBL13243602 | 0.82 | ALDH1A1 (0.46) | MCHR1ALDH1A1KDM4ETDP1HTT | |
| SCHEMBL3034263 | 0.81 | PPARG (0.53) | MCHR1ALDH1A1KDM4ETDP1HTT | |
| SCHEMBL3038767 | 0.79 | MCHR1 (0.57) | MCHR1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL14222053 | 0.75 | MEN1 (0.46) | MCHR1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL3028682 | 0.74 | MCHR1 (0.49) | MCHR1ALDH1A1KDM4ETDP1HTT | |
| SCHEMBL3028685 | 0.74 | MCHR1 (0.49) | MCHR1ALDH1A1KDM4ETDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2010-08-19 | — | — | US | claimed |
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | CCR2, CCR1, CCR5 | MCHR1 325/4885ALDH1A1 1247/4885KDM4E 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.