Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15702357 | 0.88 | PLK1 (0.64) | KMT2AMEN1MAPTTDP1ABL1 | |
| SCHEMBL14075298 | 0.86 | LTC4S (0.67) | KMT2AMEN1MAPTTDP1ABL1 | |
| SCHEMBL2269459 | 0.85 | MEN1 (0.63) | KMT2AMEN1MAPTIGF2BP2HSD17B10 | |
| SCHEMBL6359536 | 0.83 | KMT2A (0.78) | KMT2AMEN1ALDH1A1HTTPKM | |
| SCHEMBL2740434 | 0.82 | KMT2A (0.74) | KMT2AMEN1MAPTHSD17B10TDP1 | |
| SCHEMBL2269365 | 0.80 | MEN1 (0.60) | KMT2AMEN1TDP1HTTSERPINE1 | |
| SCHEMBL1954779 | 0.79 | MEN1 (0.72) | KMT2AMEN1MAPTIGF2BP2TDP1 | |
| SCHEMBL16496601 | 0.79 | SERPINE1 (0.75) | KMT2AMEN1MAPTIGF2BP2TDP1 | |
| SCHEMBL5671306 | 0.79 | KCNK2 (0.61) | KMT2AMEN1MAPTIGF2BP2TDP1 | |
| SCHEMBL12990013 | 0.77 | KMT2A (0.72) | KMT2AMEN1MAPTHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294853-A1 | Bis Aromatic Compounds for Use in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2011-12-01 | — | — | US | disclosed |
| WO-2010029300-A1 | BIS AROMATIC COMPOUNDS FOR USE IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294853-A1 | Bis Aromatic Compounds for Use in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | KMT2A 3724/4885MEN1 4133/4885MAPT 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.