Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.42 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.42 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856151 | 0.77 | PIK3CA (0.51) | POLBPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL18108512 | 0.76 | PIK3CA (0.63) | POLBPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29141989 | 0.75 | AKR1C3 (0.41) | POLBPIK3CAPIK3CDPIK3CBAKR1C3 | |
| SCHEMBL8600042 | 0.75 | SIGMAR1 (0.48) | POLBLMNA | |
| SCHEMBL4243835 | 0.74 | KDM4E (0.48) | POLBPIK3CAPIK3CDPIK3CBMTOR | |
| SCHEMBL444108 | 0.73 | GHSR (0.52) | PIK3CAPIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL2280216 | 0.73 | AKR1C3 (0.73) | POLBAKR1C3CNR2MAPTNPC1 | |
| SCHEMBL30724575 | 0.73 | AKR1C3 (0.45) | POLBPIK3CAPIK3CDPIK3CBAKR1C3 | |
| SCHEMBL27251926 | 0.73 | PIK3CD (0.46) | POLBPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL20504089 | 0.73 | PIK3CA (0.48) | PIK3CAPIK3CDPIK3CBPIK3CGAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436577-A1 | TABLET FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE | Belite Bio, Inc (US) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023097221-A1 | TABLET FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE | BELITE BIO, INC (US) | 2023-06-01 | — | — | WO | disclosed |