Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | MAPT | P10636 | 9/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 12/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.59 |
| ▸ | CHKA | P35790 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14680275 | 0.94 | MAPT (0.78) | KDM4EMAPTALOX12HTTGAA | |
| SCHEMBL30855012 | 0.88 | MAPT (0.89) | KDM4EMAPTALOX12HTTGAA | |
| SCHEMBL30855008 | 0.86 | MAPT (0.63) | KDM4EMAPTALOX12HTTGAA | |
| SCHEMBL30854966 | 0.83 | L3MBTL1 (0.62) | KDM4EMAPTALOX12HTTGAA | |
| SCHEMBL13879814 | 0.83 | L3MBTL1 (0.63) | KDM4EMAPTALOX12HTTGAA | |
| SCHEMBL30438654 | 0.82 | PRMT6 (0.58) | KDM4EMAPTALOX12HTTGAA | |
| SCHEMBL17131831 | 0.81 | MAPT (1.00) | KDM4EMAPTALOX12HTTGAA | |
| SCHEMBL2475972 | 0.81 | GAA (0.63) | KDM4EMAPTALOX12HTTGAA | |
| SCHEMBL2464412 | 0.81 | GAA (0.67) | KDM4EMAPTALOX12HTTGAA | |
| SCHEMBL19242051 | 0.80 | F2 (0.61) | KDM4EMAPTALOX12HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |