Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 14/20 | 0.63 |
| ▸ | MAPT | P10636 | 14/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 12/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 9/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 9/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.63 |
| ▸ | APP | P05067 | 1/20 | 0.63 |
| ▸ | SNCA | P37840 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11936094 | 0.85 | GAA (0.50) | GAAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL2464412 | 0.84 | GAA (0.67) | GAAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL1843773 | 0.83 | MAPT (0.80) | GAAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL2987241 | 0.82 | PRMT6 (0.58) | GAAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL11936009 | 0.81 | USP2 (0.49) | GAAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL14680275 | 0.81 | MAPT (0.78) | GAAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL11936072 | 0.81 | MAPT (0.79) | GAAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL455536 | 0.80 | MEN1 (0.50) | GAAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL5154356 | 0.80 | MEN1 (0.50) | GAAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL3422016 | 0.80 | MEN1 (0.50) | GAAMAPTKDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1752192-B1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | PROCTER & GAMBLE (US) | 2010-02-03 | — | — | EP | claimed |
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | claimed |
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | claimed |
| EP-1760072-A1 | 1,3-diaminobenzene derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | claimed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | claimed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | claimed |
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-01 | — | — | US | claimed |
| EP-1558204-B1 | MEANS FOR COLOURING KERATIN FIBRES COMPRISING 2-AMINO-5-ETHYLPHENOL | Wella GmbH (DE) | 2011-10-12 | — | — | EP | disclosed |
| US-RE41549-E1 | Dyes for keratin fibers, the dyes containing n-benzyl-p-phenylenediamine derivatives and novel n-benzyl-p-phenylenediamine derivatives | WELLA AG (DE) | 2010-08-24 | — | — | US | disclosed |
| EP-1752192-B1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | PROCTER & GAMBLE (US) | 2010-02-03 | — | — | EP | disclosed |
| US-7641702-B2 | O-Aminophenol derivatives and colorants containing said compounds | WELLA AG (DE) | 2010-01-05 | — | — | US | disclosed |
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080235882-A1 | Novel O-Aminophenol Derivatives and Colorants Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-02 | — | — | US | disclosed |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | disclosed |
| US-20050129652-A1 | Use of native zein for improving the condition of hair, and corresponding agent | WELLA AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | US | disclosed |
| US-20050011016-A1 | Means for colouring keratin fibres comprising 2-amino-5-ethylphenol | WELLA AKTIENGESELLSCHAFT (DE) | 2005-01-20 | — | — | US | disclosed |
| US-6689174-B2 | FOR OXIDATIVELY DYEING HUMAN HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-10 | — | — | US | disclosed |
| US-20020166181-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and novel n-benzyl-p-phenylenediamine-derivatives | CHASSOT LAURENT (CH) | 2002-11-14 | — | — | US | disclosed |
| EP-1226107-A1 | N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES CONTAINING COLOURING AGENTS FOR KERATIN FIBRES AND NOVEL N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2002-07-31 | — | — | EP | disclosed |
| WO-2002018318-A1 | N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES CONTAINING COLOURING AGENTS FOR KERATIN FIBRES AND NOVEL N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | KRT18, COL2A1, COL1A1 | GAA 3251/4885MAPT 317/4885KDM4E 295/4885 |
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | KRT18, DSP, DSG1 | GAA 2771/4885MAPT 1737/4885KDM4E 2209/4885 |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | KRT18, CBR3, CCNB3 | GAA 4729/4885MAPT 2990/4885KDM4E 1046/4885 |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | TACR1, KRT18, AKR1C4 | GAA 4835/4885MAPT 2140/4885KDM4E 1548/4885 |
| US-20020166181-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and novel n-benzyl-p-phenylenediamine-derivatives | KRT18, KPNB1, VIM | GAA 3243/4885MAPT 725/4885KDM4E 1175/4885 |
| US-20080235882-A1 | Novel O-Aminophenol Derivatives and Colorants Containing Said Compounds | CBR3, KRT18, F12 | GAA 4664/4885MAPT 2168/4885KDM4E 1516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.