Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | C1R | P00736 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038438 | 0.84 | MMP2 (0.52) | MAPTKMT2ALMNATDP1MAPK1 | |
| SCHEMBL3043863 | 0.84 | NPC1 (0.61) | MAPTKMT2ALMNATDP1MAPK1 | |
| SCHEMBL2252128 | 0.83 | MAPT (0.68) | MAPTKMT2ALMNATDP1L3MBTL1 | |
| SCHEMBL2402899 | 0.80 | MAPT (0.43) | MAPTKMT2ALMNATDP1MAPK1 | |
| SCHEMBL2133422 | 0.79 | AGPAT2 (0.61) | MAPTTDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL2688576 | 0.79 | HSPD1 (0.49) | MAPTKMT2ALMNATDP1MAPK1 | |
| SCHEMBL3050578 | 0.77 | MMP2 (0.64) | MAPTKMT2ALMNATDP1HTT | |
| SCHEMBL3053830 | 0.77 | NPC1 (0.55) | MAPTKMT2ALMNATDP1MAPK1 | |
| SCHEMBL2690401 | 0.76 | MMP2 (0.63) | MAPTKMT2ALMNATDP1L3MBTL1 | |
| SCHEMBL13522796 | 0.76 | KDM6B (0.73) | MAPTTDP1HTTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479282-B1 | Media including nitroreductase enzymatic substrates | BIOMERIEUX SA (FR) | 2018-03-28 | — | — | EP | disclosed |
| EP-2155893-B1 | NOVEL NITROREDUCTASE ENZYMATIC SUBSTRATES | BIOMERIEUX SA (FR) | 2016-10-19 | — | — | EP | disclosed |
| EP-2479282-A1 | Media including nitroreductase enzymatic substrates | bioMérieux (FR) | 2012-07-25 | — | — | EP | disclosed |
| US-8211662-B2 | Nitroreductase enzymatic substrates | BIOMERIEUX (FR) | 2012-07-03 | — | — | US | disclosed |
| US-20100221764-A1 | NOVEL NITROREDUCTASE ENZYMATIC SUBSTRATES | BIOMERIEUX (FR) | 2010-09-02 | — | — | US | disclosed |
| EP-2155893-A2 | NOVEL NITROREDUCTASE ENZYMATIC SUBSTRATES | BIOMERIEUX (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008152305-A2 | NOVEL NITROREDUCTASE ENZYMATIC SUBSTRATES | bioMérieux (FR) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221764-A1 | NOVEL NITROREDUCTASE ENZYMATIC SUBSTRATES | CBR1, CBR3, XDH | MAPT 4865/4885KMT2A 2837/4885LMNA 4014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.