Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7553241 | 0.71 | ALDH1A1 (0.42) | — | |
| SCHEMBL11094674 | 0.70 | ALDH1A1 (0.57) | — | |
| SCHEMBL5705770 | 0.60 | KDM4E (0.33) | KDM2BKDM4C | |
| SCHEMBL10883634 | 0.56 | MEN1 (0.37) | KDM2BKDM4C | |
| SCHEMBL7471396 | 0.55 | ALDH1A1 (0.61) | KDM2BKDM4C | |
| SCHEMBL6863454 | 0.55 | ALKBH5 (0.55) | — | |
| SCHEMBL7493780 | 0.54 | DAO (0.31) | — | |
| SCHEMBL16034780 | 0.53 | — | — | |
| SCHEMBL27359904 | 0.52 | — | — | |
| SCHEMBL10816370 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023101556-A1 | NOVEL INHIBITORS OF ASPARTATE TRANSCARBAMOYLASE (ATCASE) AND COMPOSITIONS, METHODS AND USES RELATED THERETO. | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2023-06-08 | — | — | WO | disclosed |