Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PMM2 | O15305 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11151988 | 0.85 | KMT2A (0.50) | ALDH1A1ADRB1HCAR1MAPTMEN1 | |
| SCHEMBL5705770 | 0.74 | KDM4E (0.33) | ALDH1A1TSHRKDM4E | |
| SCHEMBL15761065 | 0.73 | ADRB1 (0.43) | ALDH1A1HTTADRB1HCAR1MAPT | |
| SCHEMBL5678843 | 0.71 | POLB (0.47) | ALDH1A1HTTHCAR1MAPTMEN1 | |
| SCHEMBL30438638 | 0.71 | KDM2B (0.33) | — | |
| SCHEMBL11466957 | 0.71 | FAAH (0.33) | MGLL | |
| SCHEMBL11094674 | 0.70 | ALDH1A1 (0.57) | ALDH1A1ADRB1MAPTMEN1KMT2A | |
| SCHEMBL456557 | 0.68 | ALKBH5 (0.56) | ALDH1A1HTTADRB1MAPTMEN1 | |
| SCHEMBL17621229 | 0.66 | F2 (0.50) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL710771 | 0.66 | MGLL (0.70) | ALDH1A1ADRB1NPSR1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814488-A1 | DIMETHYLARGININE DIMETHYLAMINOHYDROLASE INHIBITORS AND METHODS OF USE THEREOF | The Board of Trustees of the Leland Stanford Junior University (US) | 2014-12-24 | — | — | EP | claimed |
| WO-2013123033-A1 | DIMETHYLARGININE DIMETHYLAMINOHYDROLASE INHIBITORS AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-08-22 | — | — | WO | claimed |
| WO-2023101556-A1 | NOVEL INHIBITORS OF ASPARTATE TRANSCARBAMOYLASE (ATCASE) AND COMPOSITIONS, METHODS AND USES RELATED THERETO. | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2023-06-08 | — | — | WO | disclosed |
| EP-2814488-A1 | DIMETHYLARGININE DIMETHYLAMINOHYDROLASE INHIBITORS AND METHODS OF USE THEREOF | The Board of Trustees of the Leland Stanford Junior University (US) | 2014-12-24 | — | — | EP | disclosed |
| WO-2014160947-A1 | DIMETHYLARGININE DIMETHYLAMINOHYDROLASE INHIBITORS AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-10-02 | — | — | WO | disclosed |
| WO-2013171755-A2 | \"COMBUSTION SYNTHESIS OF NANOCRYSTALLINE ALKALI AND ALKALINE EARTH METAL OXIDES OR MIXTURE THEREOF AND ITS APPLICATIONS IN SYNTHESIS OF [4- (ALKYL/ARYL)-OXY- 1,3 -DIOXOLANE-2- ONE] AND 2-OXAZOLIDINONES\ | YADAV GANAPATI DADASAHEB (IN) | 2013-11-21 | — | — | WO | disclosed |
| WO-2013123033-A1 | DIMETHYLARGININE DIMETHYLAMINOHYDROLASE INHIBITORS AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-08-22 | — | — | WO | disclosed |
| WO-2002053132-A1 | WATER-SOLUBLE POWDERY OR GRANULAR COMPOSITIONS BASED ON PHENANTHRIDINES AND THEIR USES | VIRBAC S.A. (FR) | 2002-07-11 | — | — | WO | disclosed |
| US-6218441-B1 | USEFUL FOR LIQUID SEPARATION PROCESSES, SUCH AS, BUT NOT LIMITED TO, MICROFILTRATION, ULTRAFILTRATION, DIALYSIS, AND REVERSE OSMOSIS | BAXTER INTERNATIONAL INC. | 2001-04-17 | — | — | US | disclosed |
| EP-0951498-A1 | MELT-SPUN POLYSULFONE SEMIPERMEABLE MEMBRANES AND METHODS FOR MAKING THE SAME | Althin Medical, Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998029478-A1 | MELT-SPUN POLYSULFONE SEMIPERMEABLE MEMBRANES AND METHODS FOR MAKING THE SAME | ALTHIN MEDICAL, INC. (US) | 1998-07-09 | — | — | WO | disclosed |
| EP-0010061-A1 | Pharmaceutical preparations containing a mollusc extract | Mc Farlane, Stuart John (NZ) | 1980-04-16 | — | — | EP | disclosed |
| EP-0007572-A1 | Pharmaceutical mixtures containing an amantadine compound | CIBA-GEIGY AG (CH) | 1980-02-06 | — | — | EP | disclosed |