Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NOX4 | Q9NPH5 | 8/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | CYBB | P04839 | 4/20 | 0.40 |
| ▸ | NOX5 | Q96PH1 | 4/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833240 | 0.77 | GAA (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL11151988 | 0.77 | KMT2A (0.50) | ALDH1A1KDM4EMAPTSMN1; SMN2NOX4 | |
| SCHEMBL9524828 | 0.76 | HCAR1 (0.39) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL4029048 | 0.73 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTSMN1; SMN2NOX4 | |
| SCHEMBL5679016 | 0.72 | MYC (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL1232067 | 0.71 | TSHR (0.48) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL13167297 | 0.70 | MAPT (0.62) | ALDH1A1KDM4EMAPTSMN1; SMN2NOX4 | |
| SCHEMBL7553241 | 0.70 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTSMN1; SMN2MGLL | |
| SCHEMBL30438638 | 0.70 | KDM2B (0.33) | — | |
| SCHEMBL4700337 | 0.70 | KDM4E (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2NOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126970-A2 | Anxiolytic and anti-depressant thienopyridine derivatives | BEECHAM GROUP PLC (GB) | 1984-12-05 | — | — | EP | disclosed |