Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159084 | 0.88 | GRM4 (0.67) | KDM4EKCNH2GRM4SMN1; SMN2HTR1A | |
| SCHEMBL10157305 | 0.88 | PIK3CA (0.57) | PIK3CAKDM4EMAPK1NPSR1LMNA | |
| Ethoxycarbonyl Group SCHEMBL28608280 | 0.86 | KDM4E (0.51) | PIK3CAKDM4EMAPK1NPSR1LMNA | |
| SCHEMBL7665284 | 0.81 | BMP4 (0.61) | KDM4ENPSR1LMNAKCNH2GRM4 | |
| SCHEMBL30251801 | 0.81 | BMP4 (0.61) | KDM4ENPSR1LMNAKCNH2GRM4 | |
| SCHEMBL27606458 | 0.81 | KDM4E (0.53) | KDM4EMAPK1NPSR1LMNAMEN1 | |
| SCHEMBL30440566 | 0.81 | GRM4 (0.56) | PIK3CAKDM4EMAPK1NPSR1GRM4 | |
| SCHEMBL27290306 | 0.80 | CLK4 (0.53) | MAPK1KCNH2GRM4KMT2ATLR8 | |
| SCHEMBL28295741 | 0.80 | TLR8 (0.51) | PIK3CAKDM4EMAPK1NPSR1LMNA | |
| SCHEMBL2051073 | 0.80 | MAP3K14 (0.57) | KDM4EMAPK1NPSR1LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183179-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF | CRESCENTA BIOSCIENCES (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183179-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF | FABP4, FABP1, FABP3 | PIK3CA 3770/4885KDM4E 2557/4885MAPK1 2881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.