Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.50 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.50 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071505 | 1.00 | KIF11 (0.55) | KIF11TTRAPPIP6K1IP6K3 | |
| SCHEMBL12408499 | 1.00 | KIF11 (0.55) | KIF11TTRAPPIP6K1IP6K3 | |
| SCHEMBL31418696 | 0.90 | KIF11 (0.45) | KIF11TTRAPPIP6K1IP6K3 | |
| SCHEMBL22804962 | 0.82 | KIF11 (0.61) | KIF11TTRAPPIP6K1IP6K3 | |
| SCHEMBL12425753 | 0.82 | HDAC1 (0.61) | KIF11 | |
| SCHEMBL12489263 | 0.80 | KIF11 (0.51) | KIF11KDM4EKMT2AMTNR1AMTNR1B | |
| SCHEMBL22203071 | 0.78 | KIF11 (0.55) | KIF11KDM4EKMT2AMTNR1AMTNR1B | |
| SCHEMBL23839435 | 0.77 | KIF11 (0.54) | KIF11KDM4EKMT2AMTNR1AMTNR1B | |
| SCHEMBL27371971 | 0.77 | TTR (0.62) | TTRAPPKDM4EKMT2ACA12 | |
| SCHEMBL32690804 | 0.77 | CCNB2 (0.44) | TTRAPPIP6K1IP6K3IP6K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11674135-B2 | DNA-encoded libraries having encoding oligonucleotide linkages not readable by polymerases | X-CHEM, INC. (US) | 2023-06-13 | — | — | US | disclosed |