Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.50 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.50 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440640 | 1.00 | KIF11 (0.55) | KIF11TTRAPPIP6K1IP6K3 | |
| SCHEMBL1071505 | 1.00 | KIF11 (0.55) | KIF11TTRAPPIP6K1IP6K3 | |
| SCHEMBL31418696 | 0.90 | KIF11 (0.45) | KIF11TTRAPPIP6K1IP6K3 | |
| SCHEMBL22804962 | 0.82 | KIF11 (0.61) | KIF11TTRAPPIP6K1IP6K3 | |
| SCHEMBL12425753 | 0.82 | HDAC1 (0.61) | KIF11 | |
| SCHEMBL12489263 | 0.80 | KIF11 (0.51) | KIF11KDM4EKMT2AMTNR1AMTNR1B | |
| SCHEMBL22203071 | 0.78 | KIF11 (0.55) | KIF11KDM4EKMT2AMTNR1AMTNR1B | |
| SCHEMBL23839435 | 0.77 | KIF11 (0.54) | KIF11KDM4EKMT2AMTNR1AMTNR1B | |
| SCHEMBL27371971 | 0.77 | TTR (0.62) | TTRAPPKDM4EKMT2ACA12 | |
| SCHEMBL32690804 | 0.77 | CCNB2 (0.44) | TTRAPPIP6K1IP6K3IP6K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481714-B2 | Light-responsive artificial nucleotide having photo-crosslinking ability | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2013-07-09 | — | — | US | disclosed |
| US-8481714-B2 | Light-responsive artificial nucleotide having photo-crosslinking ability | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2013-07-09 | — | — | US | disclosed |
| US-7972792-B2 | Sequence-specific nucleic acid purification method manner | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20110034683-A1 | SEQUENCE-SPECIFIC NUCLEIC ACID PURIFICATION METHOD MANNER | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2011-02-10 | — | — | US | disclosed |
| US-20100274000-A1 | LIGHT-RESPONSIVE ARTIFICIAL NUCLEOTIDE HAVING PHOTO-CROSSLINKING ABILITY | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274000-A1 | LIGHT-RESPONSIVE ARTIFICIAL NUCLEOTIDE HAVING PHOTO-CROSSLINKING ABILITY | NME2, NR2E3, NSUN2 | KIF11 2780/4885TTR 2857/4885APP 2763/4885 |
| US-20110034683-A1 | SEQUENCE-SPECIFIC NUCLEIC ACID PURIFICATION METHOD MANNER | UNG, LIG1, NUDT21 | KIF11 2663/4885TTR 4133/4885APP 4380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.