Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071505 | 0.80 | KIF11 (0.55) | KIF11KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL30440640 | 0.80 | KIF11 (0.55) | KIF11KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL12408499 | 0.80 | KIF11 (0.55) | KIF11KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL8125643 | 0.78 | KIF11 (0.58) | KIF11KDM4EALDH1A1GAAKMT2A | |
| Carbazole SCHEMBL11584093 | 0.75 | KIF11 (0.58) | KIF11KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL13908714 | 0.74 | CYP4F2 (0.65) | CYP4F2CYP4A11ALDH1A1MAPTRAB9A | |
| SCHEMBL13697649 | 0.74 | KDM4E (0.55) | KIF11KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL2877458 | 0.74 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1KMT2AMEN1 | |
| SCHEMBL2877454 | 0.74 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1KMT2AMEN1 | |
| SCHEMBL22804962 | 0.74 | KIF11 (0.61) | KIF11KDM4EALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7972792-B2 | Sequence-specific nucleic acid purification method manner | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20110034683-A1 | SEQUENCE-SPECIFIC NUCLEIC ACID PURIFICATION METHOD MANNER | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2011-02-10 | — | — | US | disclosed |
| US-20100274000-A1 | LIGHT-RESPONSIVE ARTIFICIAL NUCLEOTIDE HAVING PHOTO-CROSSLINKING ABILITY | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274000-A1 | LIGHT-RESPONSIVE ARTIFICIAL NUCLEOTIDE HAVING PHOTO-CROSSLINKING ABILITY | NME2, NR2E3, NSUN2 | KIF11 2780/4885CYP4F2 1330/4885CYP4A11 2420/4885 |
| US-20110034683-A1 | SEQUENCE-SPECIFIC NUCLEIC ACID PURIFICATION METHOD MANNER | UNG, LIG1, NUDT21 | KIF11 2663/4885CYP4F2 2465/4885CYP4A11 3754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.