Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.73 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.73 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29693614 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1PKN1PKN2NPC1 | |
| SCHEMBL695990 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1PKN1PKN2NPC1 | |
| SCHEMBL31592970 | 0.85 | KDM4E (0.61) | KDM4EALDH1A1PKN1PKN2HPSE | |
| SCHEMBL18616895 | 0.85 | ALDH1A1 (0.51) | KDM4EALDH1A1PKN1PKN2HPSE | |
| Hydrochloric Acid SCHEMBL18586196 | 0.84 | ALDH1A1 (0.50) | KDM4EALDH1A1PKN1PKN2HPSE | |
| SCHEMBL2178266 | 0.82 | NPC1 (0.88) | KDM4EALDH1A1PKN1PKN2HPSE | |
| SCHEMBL29386825 | 0.82 | NPC1 (0.88) | KDM4EALDH1A1PKN1PKN2HPSE | |
| SCHEMBL6532479 | 0.81 | NPC1 (0.61) | KDM4EALDH1A1PKN1PKN2HPSE | |
| SCHEMBL6532899 | 0.81 | NPC1 (0.68) | KDM4EALDH1A1PKN1PKN2HPSE | |
| SCHEMBL23999512 | 0.80 | MEN1 (0.54) | KDM4EALDH1A1PKN1PKN2HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426289-A1 | AKT3 MODULATORS | Georgiamune Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| WO-2023081845-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |