Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | PKN1 | Q16512 | 1/20 | 1.00 |
| ▸ | PKN2 | Q16513 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 0.75 |
| ▸ | RAB9A | P51151 | 7/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.67 |
| ▸ | PKM | P14618 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | LDHA | P00338 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29693614 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1PKN1PKN2NPC1 | |
| Pyridine SCHEMBL28089196 | 0.89 | NPC1 (0.82) | KDM4EALDH1A1PKN1PKN2NPC1 | |
| SCHEMBL29386825 | 0.88 | NPC1 (0.88) | KDM4EALDH1A1PKN1PKN2NPC1 | |
| SCHEMBL2178266 | 0.88 | NPC1 (0.88) | KDM4EALDH1A1PKN1PKN2NPC1 | |
| Hydrochloric Acid SCHEMBL2148025 | 0.86 | NPC1 (0.92) | KDM4EALDH1A1PKN1PKN2NPC1 | |
| Hydrochloric Acid SCHEMBL2147086 | 0.86 | NPC1 (0.92) | KDM4EALDH1A1PKN1PKN2NPC1 | |
| SCHEMBL24295036 | 0.86 | NPC1 (0.84) | KDM4EALDH1A1PKN1PKN2NPC1 | |
| Benzene SCHEMBL28005151 | 0.86 | NPC1 (1.00) | KDM4EALDH1A1PKN1PKN2NPC1 | |
| SCHEMBL105095 | 0.86 | NPC1 (1.00) | KDM4EALDH1A1PKN1PKN2NPC1 | |
| SCHEMBL30440947 | 0.85 | KDM4E (0.73) | KDM4EALDH1A1PKN1PKN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109887764-B | Electrolyte of high-nickel ternary system capacitor battery and preparation method thereof | 无锡凯帕德瑞科技有限公司 | 2021-06-25 | — | — | CN | claimed |
| EP-2421825-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2012-02-29 | — | — | EP | claimed |
| WO-2010124108-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-28 | — | — | WO | claimed |
| US-7470827-B2 | Composition for the vapor phase dehydrohalogenation of 1,1,2-trihaloethane to 1,1-dihaloethylene and methods for preparing and using such composition | PPG INDUSTRIES OHIO, INC. (US) | 2008-12-30 | — | — | US | claimed |
| US-20080242902-A1 | Composition For the Vapor Phase Dehydrohalogenation of 1,1,2-Trihaloethane To 1,1-Dihaloethylene and Methods For Preparing and Using Such Composition | PPG INDUSTRIES OHIO, INC (US) | 2008-10-02 | — | — | US | claimed |
| WO-2006132625-A1 | COMPOSITION FOR THE VAPOR PHASE DEHYDROHALOGENATION OF 1,1,2-TRIHALOETHANE TO 1,1-DIHALOETHYLENE AND METHODS FOR PREPARING AND USING SUCH COMPOSITIONS | PPG INDUSTRIES OHIO, INC. (US) | 2006-12-14 | — | — | WO | claimed |
| US-12052915-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | SAMSUNG DISPLAY CO., LTD. (KR) | 2024-07-30 | — | — | US | disclosed |
| EP-4019607-B1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INT (FR) | 2024-05-15 | — | — | EP | disclosed |
| US-11935803-B2 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-03-19 | — | — | US | disclosed |
| CN-117567431-A | Benzimidazole compound, preparation method thereof and organic weldable protective agent | 深圳市贝加电子材料有限公司 | 2024-02-20 | — | — | CN | disclosed |
| US-20240052235-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (FR) | 2024-02-15 | — | — | US | disclosed |
| CN-116783168-A | Electrochromic compounds and optical articles comprising the same | 依视路国际公司 | 2023-09-19 | — | — | CN | disclosed |
| US-20230292595-A1 | Organic Light Emitting Diode and Device Comprising the Same | NOVALED GMBH (DE) | 2023-09-14 | — | — | US | disclosed |
| WO-2006132625-A1 | COMPOSITION FOR THE VAPOR PHASE DEHYDROHALOGENATION OF 1,1,2-TRIHALOETHANE TO 1,1-DIHALOETHYLENE AND METHODS FOR PREPARING AND USING SUCH COMPOSITIONS | PPG INDUSTRIES OHIO, INC. (US) | 2006-12-14 | — | — | WO | disclosed |
| US-5849765-A | Tetrahydropyridine derivatives as dopamine receptor subtype ligands | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-15 | — | — | US | disclosed |
| US-5026705-A | Benzimidazolylpyridazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-06-25 | — | — | US | disclosed |
| US-4923869-A | INOTROPIC, VASODILATING, AND ANTITHROMBOTIC AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-05-08 | — | — | US | disclosed |
| EP-0193013-B1 | BENZIMIDAZOLYL-PYRIDAZINONES | MERCK PATENT GmbH (DE) | 1989-04-19 | — | — | EP | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |
| EP-0193013-A2 | Benzimidazolyl-pyridazinones | MERCK PATENT GmbH (DE) | 1986-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12052915-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | BMI1, L1CAM, EML4 | KDM4E 375/4885ALDH1A1 271/4885PKN1 1761/4885 |
| US-20240052235-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | EYA3, LAGE3, CDKL5 | KDM4E 1272/4885ALDH1A1 2987/4885PKN1 478/4885 |
| US-20080242902-A1 | Composition For the Vapor Phase Dehydrohalogenation of 1,1,2-Trihaloethane To 1,1-Dihaloethylene and Methods For Preparing and Using Such Composition | CYP2E1, CYP1A1, HDHD5 | KDM4E 865/4885ALDH1A1 73/4885PKN1 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.