Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.60 |
| ▸ | CTSL | P07711 | 4/20 | 0.58 |
| ▸ | CTSB | P07858 | 4/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.58 |
| ▸ | CTSK | P43235 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825534 | 0.89 | CAPN1 (0.74) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL8617156 | 0.88 | TACR1 (0.61) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7293242 | 0.86 | TACR1 (0.60) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7293246 | 0.86 | TACR1 (0.60) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL6330507 | 0.86 | TACR1 (0.62) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7327386 | 0.86 | TACR1 (0.62) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL8699187 | 0.86 | TACR1 (0.65) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7165055 | 0.86 | CTSK (0.66) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL29550348 | 0.85 | TACR1 (0.64) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7318249 | 0.84 | ITGB3 (0.60) | TACR1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012153125-A1 | NOVEL COMPOUNDS AND METHODS FOR USE IN MEDICINE | ASTON UNIVERSITY (GB) | 2012-11-15 | — | — | WO | disclosed |
| US-7723307-B2 | Amino acid derivatives and pharmaceutical uses thereof | ASTON UNIVERSITY (GB) | 2010-05-25 | — | — | US | disclosed |
| US-20080200511-A1 | Novel Compounds and Methods of Using the Same | ASTON UNIVERSITY (GB) | 2008-08-21 | — | — | US | disclosed |
| EP-1648924-B1 | DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME | UNIV ASTON (GB) | 2008-07-30 | — | — | EP | disclosed |
| EP-1648924-A2 | DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME | The Nottingham Trent University (GB) | 2006-04-26 | — | — | EP | disclosed |
| WO-2004113363-A2 | DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME | THE NOTTINGHAM TRENT UNIVERSITY (GB) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200511-A1 | Novel Compounds and Methods of Using the Same | F3, IL4I1, TPMT | TACR1 896/4885CTSL 2160/4885CTSB 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.