Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.62 |
| ▸ | CTSL | P07711 | 3/20 | 0.61 |
| ▸ | CTSB | P07858 | 2/20 | 0.61 |
| ▸ | CTSS | P25774 | 2/20 | 0.61 |
| ▸ | CTSK | P43235 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.58 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.54 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330507 | 1.00 | TACR1 (0.62) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL6195776 | 0.87 | CASP1 (0.69) | — | |
| SCHEMBL7416573 | 0.87 | CASP1 (0.69) | — | |
| SCHEMBL28356104 | 0.87 | TACR1 (0.64) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7318249 | 0.86 | ITGB3 (0.60) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7327056 | 0.86 | ITGB3 (0.60) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL3044116 | 0.86 | TACR1 (0.60) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL13998432 | 0.86 | CTSL (0.64) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL6439753 | 0.86 | TACR1 (0.62) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL4980616 | 0.86 | TACR1 (0.62) | TACR1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047400-A | Treatment of infection; antitumor agents | ADIR ET CIE (FR) | 1991-09-10 | — | — | US | disclosed |
| EP-0292800-A2 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0129163-B1 | ARPHAMENINE AND ITS RELATED COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1987-09-16 | — | — | EP | disclosed |
| EP-0129163-A1 | Arphamenine and its related compounds, a process for their preparation and their use as medicaments | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1984-12-27 | — | — | EP | disclosed |