Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | MARS1 | P56192 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25187350 | 1.00 | NPSR1 (0.44) | NPSR1GAALMNATP53NPBWR1 | |
| SCHEMBL25479342 | 0.91 | KDM4E (0.47) | NPSR1GAATP53NPBWR1MCHR1 | |
| SCHEMBL25174338 | 0.86 | LMNA (0.46) | NPSR1GAALMNATP53NPBWR1 | |
| SCHEMBL25479257 | 0.82 | NPSR1 (0.49) | NPSR1GAALMNATP53NPBWR1 | |
| SCHEMBL25479890 | 0.81 | ALDH1A1 (0.52) | NPSR1GAALMNATP53NPBWR1 | |
| SCHEMBL9227950 | 0.80 | NPSR1 (0.51) | NPSR1GAALMNATP53NPBWR1 | |
| SCHEMBL25174337 | 0.77 | KDM4E (0.46) | NPSR1GAALMNATP53NPBWR1 | |
| SCHEMBL25479341 | 0.73 | KDM4E (0.46) | NPSR1GAALMNATP53NPBWR1 | |
| SCHEMBL9230980 | 0.72 | NPSR1 (0.53) | NPSR1GAALMNATP53NPBWR1 | |
| SCHEMBL9228112 | 0.72 | NPSR1 (0.58) | NPSR1GAALMNATP53NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429663-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | Vigil Neuroscience, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086799-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |