Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588034 | 0.79 | HCRTR1 (0.46) | GBA1HPGDHTTTSHRCNR1 | |
| SCHEMBL30367514 | 0.78 | L3MBTL3 (0.41) | GBA1ALDH1A1HPGDHTTTSHR | |
| SCHEMBL16093639 | 0.77 | SMN1; SMN2 (0.46) | GBA1ALDH1A1HPGDHTTTSHR | |
| SCHEMBL30442465 | 0.75 | HPGD (0.53) | ALDH1A1HPGDHTTSPRRAB9A | |
| SCHEMBL30441997 | 0.75 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EHTTTSHR | |
| SCHEMBL30367109 | 0.75 | SPR (0.39) | HPGDTSHRCNR1SPRNPC1 | |
| SCHEMBL30530971 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTTLMNAL3MBTL1 | |
| SCHEMBL15058808 | 0.73 | RXFP1 (0.62) | ALDH1A1HPGDKDM4EHTTRAB9A | |
| SCHEMBL12569518 | 0.72 | CNR1 (0.51) | ALDH1A1KDM4EHTTTSHRCNR1 | |
| SCHEMBL12082834 | 0.72 | GABRD (0.63) | ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113773289-B | Naphthalene [1,2-b ] heterocycle-4, 5-diketone compound and preparation method and application thereof | 沈阳药科大学 | 2023-05-12 | — | — | CN | disclosed |