SCHEMBL3044265

SCHEMBL3044265

C=C(C)C(=O)Nc1ccc(Cl)cc1C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.71
HSD17B10 Q99714 2/20 0.71
SERPINE1 P05121 8/20 0.55
AKR1C4 P17516 1/20 0.52
AKR1C3 P42330 1/20 0.52
AKR1C2 P52895 1/20 0.52
AKR1C1 Q04828 1/20 0.52
PPARG P37231 1/20 0.51
PPARA Q07869 1/20 0.51
GAA P10253 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
ACLY P53396 1/20 0.48
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.47
KCNK2 O95069 1/20 0.47
KCNK10 P57789 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1308628 0.86 KDM4E (0.62) KDM4EHSD17B10SERPINE1AKR1C4AKR1C3
SCHEMBL19253255 0.84 MAPT (0.64) SERPINE1GAAALDH1A1TP53
SCHEMBL30661117 0.84 MAPT (0.64) SERPINE1GAAALDH1A1TP53
SCHEMBL5409391 0.84 TDP1 (0.55) KDM4EHSD17B10CA12CA1CA2
SCHEMBL7988908 0.83 KDM4E (0.70) KDM4EHSD17B10SERPINE1AKR1C4AKR1C3
SCHEMBL7045036 0.83 KDM4E (1.00) KDM4EHSD17B10SERPINE1AKR1C4AKR1C3
SCHEMBL28534851 0.82 USP2 (0.55) KDM4EGAAALDH1A1TP53
SCHEMBL14339913 0.81 POLB (0.56) KDM4EHSD17B10AKR1C4AKR1C3AKR1C2
SCHEMBL19268075 0.80 GABRP (0.63) KDM4EHSD17B10SERPINE1ALDH1A1TP53
SCHEMBL19268087 0.80 TP53 (0.54) KDM4EHSD17B10SERPINE1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE41579-E1 Positive type photosensitive image-forming material for use with an infrared laser FUJIFILM CORPORATION (JP) 2010-08-24 US disclosed
EP-1219464-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2008-02-13 EP disclosed
EP-1437232-B1 A positive type photosensitive image-forming material for an infrared laser and a positive type photosensitive composition for an infrared laser FUJI PHOTO FILM CO LTD (JP) 2007-01-03 EP disclosed
US-6890700-B2 Capable of plate-making by scanning exposure based on digital signals, high sensitivity, free of residual color and residual film phenomena, and excellent in resistance to smearing (i.e., staining) and excellent in press life FUJI PHOTO FILM CO., LTD. (JP) 2005-05-10 US disclosed
EP-1258369-B1 A positive type photosensitive image-forming material for an infrared laser and a positive type photosensitive composition for an infrared laser FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
EP-1452312-A1 A positive type photosensitive image-forming material for an infrared laser and a positive type photosensitive composition for an infrared laser FUJI PHOTO FILM CO., LTD. (JP) 2004-09-01 EP disclosed
EP-1452335-A1 A positive type photosensitive image-forming material for an infrared laser and a positive type photosensitive composition for an infrared laser FUJI PHOTO FILM CO., LTD. (JP) 2004-09-01 EP disclosed
EP-1449655-A1 A positive type photosensitive image-forming material for an infrared laser and a positive type photosensitive composition for an infrared laser FUJI PHOTO FILM CO., LTD. (JP) 2004-08-25 EP disclosed
EP-1449654-A1 A positive type photosensitive image-forming material for an infrared laser and a positive composition for an infrared laser and a positive type photosensitive composition for an infrared laser FUJI PHOTO FILM CO., LTD. (JP) 2004-08-25 EP disclosed
EP-1437232-A2 A positive type photosensitive image-forming material for an infrared laser and a positive type photosensitive composition for an infrared laser FUJI PHOTO FILM CO., LTD. (JP) 2004-07-14 EP disclosed
US-6423467-B1 USEFUL IN A LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 2002-07-23 US disclosed
US-20020086233-A1 Useful in a lithographic printing plates FUJIFILM CORPORATION (JP) 2002-07-04 US disclosed
EP-1219464-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-07-03 EP disclosed
US-20020081522-A1 Positive type photosensitive image-forming material for an infrared laser and a positive type photosensitive composition for an infrared laser FUJIFILM CORPORATION (JP) 2002-06-27 US disclosed
US-20020051929-A1 Using a fluorine-containing polymer in the photosensitive resin composition to give high contrast of printing plate image while maintaining press life FUJIFILM CORPORATION (JP) 2002-05-02 US disclosed
US-6340551-B1 ARE CAPABLE OF DIRECTLY MAKING A PRINTING PLATE USING AN INFRARED LASER BASED ON DIGITAL SIGNALS OUTPUTTED FROM A COMPUTER FUJI FILM CO., LTD. (JP) 2002-01-22 US disclosed
US-6238839-B1 DIMENSIONALLY STABLE METAL SUPPORT COATED WITH A HEAT-INSULATING LAYER, A HYDROPHILIC LAYER AND A THERMOSENSITIVE LIPOPHILIC LAYER; IMAGE QUALITY, MULTICOLOR PRINTS FUJI PHOTO FILM CO., LTD. (JP) 2001-05-29 US disclosed
EP-1078736-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-02-28 EP disclosed
EP-0949539-A2 Photosensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 1999-10-13 EP disclosed
EP-0909657-A2 A positive type photosensitive image-forming material for an infrared laser and a positive type photosensitive composition for an infrared laser FUJI PHOTO FILM CO., LTD (JP) 1999-04-21 EP disclosed