SCHEMBL4094573

SCHEMBL4094573

O=C(O)c1ccc(Nc2nc(Cl)nc(Cl)n2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.61
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
POLB P06746 1/20 0.58
MEN1 O00255 3/20 0.56
MAPT P10636 3/20 0.56
KMT2A Q03164 3/20 0.56
MAPK1 P28482 1/20 0.56
AURKA O14965 4/20 0.55
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CACNA1B Q00975 1/20 0.54
APBA1 Q02410 1/20 0.54
PDE4B Q07343 5/20 0.53
TXN P10599 1/20 0.53
PDE4D Q08499 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304437 0.96 POLB (0.63) NFKB1NPC1RAB9ASMN1; SMN2POLB
SCHEMBL3793508 0.89 POLB (0.59) NFKB1NPC1RAB9ASMN1; SMN2POLB
SCHEMBL1023029 0.87 NPC1 (0.71) NPC1RAB9ASMN1; SMN2MEN1MAPT
SCHEMBL29874885 0.85 NPC1 (0.69) NPC1RAB9ASMN1; SMN2MEN1MAPT
SCHEMBL24942659 0.85 AURKA (0.59) NPC1RAB9ASMN1; SMN2AURKAPDE4B
SCHEMBL6673841 0.84 CA12 (0.57) NFKB1SMN1; SMN2POLBMEN1MAPT
SCHEMBL8911586 0.84 NPC1 (0.66) NFKB1NPC1RAB9ASMN1; SMN2POLB
SCHEMBL11837292 0.82 NFKB1 (0.78) NFKB1NPC1RAB9ASMN1; SMN2POLB
SCHEMBL1552406 0.82 NFKB1 (0.52) NFKB1NPC1RAB9ASMN1; SMN2POLB
SCHEMBL23321477 0.82 POLB (0.68) NFKB1NPC1SMN1; SMN2POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081798-A Preparation method of ultraviolet absorber HEB 合肥诺信生物技术有限公司 2025-06-03 CN disclosed
CN-119350261-A Preparation method of diethyl hexyl butyryl amino triazinone 天津利安隆新材料股份有限公司 2025-01-24 CN disclosed
CN-110229113-B Preparation method of ultraviolet absorbent HEB 湖北师范大学 2022-08-12 CN disclosed
EP-2633086-B1 NON-METAL TANNING PROCESS STAHL INT B V (NL) 2017-08-16 EP disclosed
EP-2838885-B1 TRIAZINE DERIVATIVES 3V SIGMA SPA (IT) 2017-02-15 EP disclosed
US-9221986-B2 Self-dispersing particles and methods for making and using the same SENSIENT COLORS LLC (US) 2015-12-29 US disclosed
US-9221986-B2 Self-dispersing particles and methods for making and using the same SENSIENT COLORS LLC (US) 2015-12-29 US disclosed
EP-2838885-A1 TRIAZINE DERIVATIVES 3V SIGMA S.p.A (IT) 2015-02-25 EP disclosed
US-8895731-B2 Triazine derivatives 3V SIGMA S.P.A. (IT) 2014-11-25 US disclosed
EP-2759539-A1 Triazine oligomers as photostabilising agents 3V SIGMA S.p.A (IT) 2014-07-30 EP disclosed
US-20100251932-A1 SELF-DISPERSING PARTICLES AND METHODS FOR MAKING AND USING THE SAME SENSIENT COLORS LLC 2010-10-07 US disclosed
US-20090241265-A1 ANTISTATIC FIBROUS MATERIAL AND METHOD FOR MANUFACTURING SAME KANEISHA CO., LTD (JP) 2009-10-01 US disclosed
US-20090050014-A1 SELF-DISPERSED PIGMENTS AND METHODS FOR MAKING AND USING THE SAME SENSIENT COLORS INC. (US) 2009-02-26 US disclosed
US-20090050014-A1 SELF-DISPERSED PIGMENTS AND METHODS FOR MAKING AND USING THE SAME SENSIENT COLORS INC. (US) 2009-02-26 US disclosed
WO-2006064574-A1 ANTISTATIC FIBROUS MATERIAL AND METHOD FOR MANUFACTURING SAME KANEHISA CO., LTD. (JP) 2006-06-22 WO disclosed
US-4939243-A Water-soluble copper complex disazo compounds containg a chloro triazinylamino group and a group of the vinylsulfone series as fiber-reactive groups and their dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-03 US disclosed
EP-0084849-B1 WATER SOLUBLE COPPER COMPLEXES OF DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1986-05-14 EP disclosed
EP-0084849-A2 Water soluble copper complexes of disazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-08-03 EP disclosed
US-4092243-A CONTAINING TRIAZINE RINGS, SELECTIVE ABSORPTION OF HYDROCARBONS BAYER AKTIENGESELLSCHAFT (DT) 1978-05-30 US disclosed
US-3957728-A MODIFIED WITH S-TRIAZINES; ABSORBENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100251932-A1 SELF-DISPERSING PARTICLES AND METHODS FOR MAKING AND USING THE SAME ZYX, NPM1, SPIN2B NFKB1 2403/4885NPC1 566/4885RAB9A 2105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.