Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3040298 | 0.89 | BDKRB1 (0.31) | — | |
| SCHEMBL3050607 | 0.85 | HSD11B1 (0.33) | OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL3038218 | 0.85 | VSIR (0.35) | VSIROPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL3038221 | 0.85 | VSIR (0.35) | VSIROPRM1OPRK1 | |
| SCHEMBL3047256 | 0.85 | HSD11B1 (0.32) | — | |
| SCHEMBL3050325 | 0.84 | HSD11B1 (0.33) | — | |
| SCHEMBL3048636 | 0.82 | HSD11B1 (0.33) | OPRM1OPRK1 | |
| SCHEMBL3043808 | 0.82 | POLB (0.33) | OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL3048392 | 0.82 | VSIR (0.38) | VSIRPRMT5OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL3047280 | 0.82 | VSIR (0.36) | VSIRPRMT5OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222345-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS | SMITHKLINE BEECHAM CORPORATION | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222345-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS | OPRL1, OPRM1, OPRK1 | VSIR 2044/4885PRMT5 2811/4885OPRM1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.