SCHEMBL30445486

SCHEMBL30445486

c1ccc2c(CP(C34CC5CC(CC(C5)C3)C4)C34CC5CC(CC(C5)C3)C4)c(CP(C34CC5CC(CC(C5)C3)C4)C34CC5CC(CC(C5)C3)C4)ccc2c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP2D6 P10635 2/20 0.32
ALDH1A1 P00352 7/20 0.31
MAPT P10636 4/20 0.31
KDM4E B2RXH2 3/20 0.31
GAA P10253 2/20 0.31
TAAR1 Q96RJ0 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
CYP2A6 P11509 1/20 0.31
TSHR P16473 1/20 0.31
G6PD P11413 1/20 0.30
PKM P14618 1/20 0.30
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3685302 1.00 HSD17B10 (0.33) HSD17B10CYP1A2CYP2C9CYP2C19CYP2D6
SCHEMBL727665 0.84 CYP2D6 (0.44) CYP1A2CYP2C9CYP2C19CYP2D6ALDH1A1
SCHEMBL1734830 0.78 P2RX7 (0.39) ALDH1A1TSHRHPGDEPHX2MEN1
SCHEMBL2830096 0.76 P2RX7 (0.38) ALDH1A1TSHRHPGDEPHX2MEN1
SCHEMBL3798533 0.71 HSD17B10 (0.33) HSD17B10CYP1A2CYP2C9CYP2C19CYP2D6
SCHEMBL3000346 0.70 P2RX7 (0.34) ALDH1A1MAPTTDP1TSHRG6PD
SCHEMBL289717 0.70 OPRK1 (0.42) ALDH1A1TSHRHPGDEPHX2MEN1
SCHEMBL3007963 0.70 CNR2 (0.39) ALDH1A1MAPT
SCHEMBL16525120 0.69 CYP11B1 (0.33) NPSR1MEN1KMT2A
SCHEMBL3005852 0.69 MEN1 (0.38) ALDH1A1MAPTTSHRNPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116139939-A Catalyst system and method for carbonylation reaction 浙江新和成股份有限公司 2023-05-23 CN disclosed