Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445486 | 1.00 | HSD17B10 (0.33) | HSD17B10CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL727665 | 0.84 | CYP2D6 (0.44) | CYP1A2CYP2C9CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL1734830 | 0.78 | P2RX7 (0.39) | ALDH1A1TSHRHPGDEPHX2MEN1 | |
| SCHEMBL2830096 | 0.76 | P2RX7 (0.38) | ALDH1A1TSHRHPGDEPHX2MEN1 | |
| SCHEMBL3798533 | 0.71 | HSD17B10 (0.33) | HSD17B10CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL3000346 | 0.70 | P2RX7 (0.34) | ALDH1A1MAPTTDP1TSHRG6PD | |
| SCHEMBL289717 | 0.70 | OPRK1 (0.42) | ALDH1A1TSHRHPGDEPHX2MEN1 | |
| SCHEMBL3007963 | 0.70 | CNR2 (0.39) | ALDH1A1MAPT | |
| SCHEMBL16525120 | 0.69 | CYP11B1 (0.33) | NPSR1MEN1KMT2A | |
| SCHEMBL3005852 | 0.69 | MEN1 (0.38) | ALDH1A1MAPTTSHRNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767864-B2 | Process for the hydroformylation of ethylenically unsaturated compounds | LUCITE INTERNATIONAL UK LIMITED (GB) | 2010-08-03 | — | — | US | claimed |
| EP-1527038-B1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS | LUCITE INT UK LTD (GB) | 2010-03-17 | — | — | EP | claimed |
| US-20080051475-A1 | Process for the Hydroformylation of Ethylenically Unsaturated Compounds | LUCITE INTERNATIONAL UK LIMITED (GB) | 2008-02-28 | — | — | US | claimed |
| EP-1565425-B1 | Production process of a lactate ester or acid | LUCITE INT UK LTD (GB) | 2008-02-20 | — | — | EP | claimed |
| US-7265240-B2 | With CO in the presence of a source of hydroxyl groups (water or an alcohol) and a catalyst obtained by combining a Group VIII metal or a compound thereof and a bidentate phosphine, e.g., tri(dibenzylideneacetone)di-palladium | LUCITE INTERNATIONAL UK LIMITED (GB) | 2007-09-04 | — | — | US | claimed |
| US-20060128985-A1 | Carbonylation of vinyl acetate | LUCITE INTERNATIONAL, INC. | 2006-06-15 | — | — | US | claimed |
| US-20060122435-A1 | Process for the carbonylation of ethylenically unsaturated compounds | LUCITE INTERNATIONAL UK LIMITED (GB) | 2006-06-08 | — | — | US | claimed |
| EP-1651587-A1 | PROCESS FOR THE HYDROFORMYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | Lucite International UK Limited (GB) | 2006-05-03 | — | — | EP | claimed |
| JP-2006508162-A | — | — | 2006-03-09 | — | — | JP | claimed |
| EP-1565425-A1 | CARBONYLATION OF VINYL ACETATE | Lucite International UK Limited (GB) | 2005-08-24 | — | — | EP | claimed |
| WO-2005003070-A1 | PROCESS FOR THE HYDROFORMYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2005-01-13 | — | — | WO | claimed |
| WO-2004050599-A1 | CARBONYLATION OF VINYL ACETATE | LUCITE INTERNATIONAL UK LIMITED (GB) | 2004-06-17 | — | — | WO | claimed |
| US-7767864-B2 | Process for the hydroformylation of ethylenically unsaturated compounds | LUCITE INTERNATIONAL UK LIMITED (GB) | 2010-08-03 | — | — | US | disclosed |
| EP-1527038-B1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS | LUCITE INT UK LTD (GB) | 2010-03-17 | — | — | EP | disclosed |
| EP-1534427-B1 | AN ADAMANTYL CATALYST SYSTEM | LUCITE INT UK LTD (GB) | 2009-10-21 | — | — | EP | disclosed |
| US-7371705-B2 | Phospha-adamantane(s) catalytic system | LUCITE INTERNATIONAL UK LIMITED (GB) | 2008-05-13 | — | — | US | disclosed |
| EP-1651587-A1 | PROCESS FOR THE HYDROFORMYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | Lucite International UK Limited (GB) | 2006-05-03 | — | — | EP | disclosed |
| EP-1565425-A1 | CARBONYLATION OF VINYL ACETATE | Lucite International UK Limited (GB) | 2005-08-24 | — | — | EP | disclosed |
| WO-2005003070-A1 | PROCESS FOR THE HYDROFORMYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2005-01-13 | — | — | WO | disclosed |
| WO-2004050599-A1 | CARBONYLATION OF VINYL ACETATE | LUCITE INTERNATIONAL UK LIMITED (GB) | 2004-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128985-A1 | Carbonylation of vinyl acetate | PCCA, LDHA, PC | HSD17B10 105/4885CYP1A2 296/4885CYP2C9 239/4885 |
| US-20080051475-A1 | Process for the Hydroformylation of Ethylenically Unsaturated Compounds | ETV6, DHPS, ELOVL6 | HSD17B10 1005/4885CYP1A2 883/4885CYP2C9 190/4885 |
| US-20060122435-A1 | Process for the carbonylation of ethylenically unsaturated compounds | CYC1, CYCS, COX5A | HSD17B10 628/4885CYP1A2 144/4885CYP2C9 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.