Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 5/20 | 0.47 |
| ▸ | NMT2 | O60551 | 4/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29599848 | 0.90 | NMT1 (0.48) | NMT1NMT2OPRL1TLR2 | |
| SCHEMBL30445612 | 0.88 | NMT1 (0.49) | NMT1NMT2TERTSLC6A5GSR | |
| SCHEMBL30828464 | 0.87 | FOLH1 (0.48) | NMT1NMT2TERTSLC6A5GSR | |
| SCHEMBL3896673 | 0.87 | GNAI3 (0.42) | NMT1NMT2TERTOPRL1GSR | |
| SCHEMBL5697801 | 0.87 | GNAI3 (0.42) | NMT1NMT2TERTOPRL1GSR | |
| SCHEMBL30572897 | 0.86 | OPRL1 (0.44) | NMT1NMT2OPRL1OPRD1OPRM1 | |
| SCHEMBL31668833 | 0.86 | FURIN (0.43) | NMT1NMT2OPRL1OPRD1OPRM1 | |
| SCHEMBL29895299 | 0.85 | NMT1 (0.49) | NMT1NMT2TERTSLC6A5GSR | |
| SCHEMBL30830406 | 0.85 | NMT2 (0.44) | NMT1NMT2SLC6A5SIRT6SIRT1 | |
| SCHEMBL31433376 | 0.85 | FOLH1 (0.46) | NMT1NMT2TERTSLC6A5GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230302123-A1 | REPLICATION-DEFICIENT ADENOVIRUS | LEIBNIZ-INSTITUT FÜR VIROLOGIE (DE) | 2023-09-28 | — | — | US | disclosed |
| EP-4188939-A1 | REPLICATION-DEFICIENT ADENOVIRUS | Leibniz-Institut für Virologie (DE) | 2023-06-07 | — | — | EP | disclosed |