SCHEMBL30445813

CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CN=[N+]=[N-])O[C@H]1n1cnc2c(NC(=O)c3ccccc3)ncnc21

nearest known ligand 0.52

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	PRMT6	Q96LA8	1/20	0.49

▸	P2RY12	Q9H244	7/20	0.45

▸	AHCY	P23526	1/20	0.43

▸	P2RY2	P41231	1/20	0.43

▸	P2RY1	P47900	1/20	0.43

▸	P2RY6	Q15077	1/20	0.43

▸	BMPR1B	O00238	1/20	0.42

▸	DNPH1	O43598	2/20	0.42

▸	ADORA1	P30542	1/20	0.41

▸	ADORA3	P0DMS8	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22206837	1.00	PRMT6 (0.49)	PRMT6P2RY12AHCYP2RY2P2RY1
SCHEMBL19927469	0.94	PRMT6 (0.49)	PRMT6P2RY12AHCYP2RY2P2RY1
SCHEMBL19927301	0.91	PRMT6 (0.46)	PRMT6P2RY12AHCYP2RY2P2RY1
SCHEMBL19927246	0.90	PRMT6 (0.45)	PRMT6P2RY12AHCYP2RY2P2RY1
SCHEMBL19927242	0.90	PRMT6 (0.45)	PRMT6P2RY12AHCYP2RY2P2RY1
SCHEMBL7032101	0.88	PRMT6 (0.51)	PRMT6P2RY12ADORA1ADORA3
SCHEMBL8937133	0.88	PRMT6 (0.51)	PRMT6P2RY12ADORA1ADORA3
SCHEMBL30446733	0.88	PRMT6 (0.51)	PRMT6P2RY12ADORA1ADORA3
SCHEMBL30446674	0.88	PRMT6 (0.54)	PRMT6P2RY12P2RY2P2RY1P2RY6
SCHEMBL22206829	0.88	PRMT6 (0.54)	PRMT6P2RY12P2RY2P2RY1P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-111434671-B	Liver-specific AMPK agonist and preparation method and application thereof	凯思凯迪（上海）医药科技有限公司	2023-07-11	—	—	CN	disclosed